2024


  1. Röthe J, Kraft R, Ricken A, Kaczmarek I, Matz-Soja M, Winter K, Dietzsch AN, Buchold J, Ludwig MG, Liebscher I, Schöneberg T, Thor D (2024). The adhesion GPCR GPR116/ADGRF5 has a dual function in pancreatic islets regulating somatostatin release and islet development. Commun Biol, 7, 104.
     
  2. Vieira Contreras F, Auger GM, Müller L, Richter V, Huetteroth W, Seufert F, Hildebrand PW, Scholz N, Thum AS, Ljaschenko D, Blanco-Redondo B, Langenhan T (2024). The adhesion G-protein-coupled receptor mayo/CG11318 controls midgut development in Drosophila. Cell Rep, 43, 113640.
     
  3. Buhlan M, Ljaschenko D, Scholz N, Langenhan T (2024). Experimental modulation of physiological force application on leg joint neurons in intact Drosophila melanogaster. Nat Protoc, 19, 113-126.
     
  4. Beckers CJ, Mrestani A, Komma F, Dannhäuser S (2024). Versatile Endogenous Editing of GluRIIA in Drosophila melanogaster. Cells, 13, 323.
     
  5. Chung YK, Chan HY, Lee TY, Wong YH (2024). Inhibition of adenylyl cyclase by GTPase-deficient G?(i) is mechanistically different from that mediated by receptor-activated G?(i). Cell Commun Signal, 22, 218.
     
  6. Schön JL, Groß VE, Post WB, Daum A, Matú? D, Pilz J, Schnorr R, Horn S, Bäumers M, Weidtkamp-Peters S, Hughes S, Schöneberg T, Prömel S (2024). The adhesion GPCR and PCP component flamingo (FMI-1) alters body size and regulates the composition of the extracellular matrix. Matrix Biol, 128, 1-10.
     
  7. Kuhn CK, Stenzel U, Berndt S, Liebscher I, Schöneberg T, Horn S (2024). The repertoire and structure of adhesion GPCR transcript variants assembled from publicly available deep-sequenced human samples. Nucleic Acids Res, 52, 3823-3836.
     
  8. Langenhan T (2024). Modularization of adhesion G protein-coupled receptor (aGPCR) structure: how alternative splicing regulates synaptogenesis. Signal Transduct Target Ther, 9, 106.
     
  9. Dietzsch AN, Al-Hasani H, Altschmied J, Bottermann K, Brendler J, Haendeler J, Horn S, Kaczmarek I, Körner A, Krause K, Landgraf K, Le Duc D, Lehmann L, Lehr S, Pick S, Ricken A, Schnorr R, Schulz A, Strnadová M, Velluva A, Zabri H, Schöneberg T, Thor D, Prömel S (2024). Dysfunction of the adhesion G protein-coupled receptor latrophilin 1 (ADGRL1/LPHN1) increases the risk of obesity. Signal Transduct Target Ther, 9, 103.
     
  10. Olbrich A, Niemeyer J, Seiffert H, Ebel S, Gros O, Lordick F, Forstmeyer D, Seehofer D, Rademacher S, Denecke T, Matz-Soja M, Berg T, van Bömmel F (2024). The GALAD score and the BALAD-2 score correlate with transarterial and systemic treatment response and survival in patients with hepatocellular carcinoma. J Cancer Res Clin Oncol, 150, 81.
     
  11. Baker DN, Abueg L, Escalona M, Farquharson KA, Lanyon JM, Le Duc D, Schöneberg T, Absolon D, Sims Y, Fedrigo O, Jarvis ED, Belov K, Hogg CJ, Shapiro B (2024). A chromosome-level genome assembly for the dugong (Dugong dugon). J Hered, 115, 212-220.
     


    12. 2023


  12. Thor D, Liebscher I (2023). Adhesion G protein-coupled receptors-Structure and functions. Prog Mol Biol Transl Sci, 195, 1-25.
     
  13. Mrestani A, Lichter K, Sirén AL, Heckmann M, Paul MM, Pauli M (2023). Single-Molecule Localization Microscopy of Presynaptic Active Zones in Drosophila melanogaster after Rapid Cryofixation. Int J Mol Sci, 24, 2128.
     
  14. Kuhn C, Boeschen M, Philip M, Schöneberg T, Thor D, Horn S (2023). Candidate drugs associated with sensitivity of cancer cell lines with DLST amplification or high mRNA levels. Oncotarget, 14, 14-20.
     
  15. Philip M, Puppel SH, Stiller M, Paschen A, Roesch A, Zaremba A, Schadendorf D, Horn S (2023). Database for queries of melanoma cohorts with molecular and clinical data. Pigment Cell Melanoma Res, 36, 252-258.
     
  16. Liebing AD, Krumbholz P, Stäubert C (2023). Protocol to characterize G(i/o) and G(s) protein-coupled receptors in transiently transfected cells using ELISA and cAMP measurements. STAR Protoc, 4, 102120.
     
  17. Scholz N, Dahse AK, Kemkemer M, Bormann A, Auger GM, Vieira Contreras F, Ernst LF, Staake H, Körner MB, Buhlan M, Meyer-Mölck A, Chung YK, Blanco-Redondo B, Klose F, Jarboui MA, Ljaschenko D, Bigl M, Langenhan T (2023). Molecular sensing of mechano- and ligand-dependent adhesion GPCR dissociation. Nature, 615(7954), 945-953.
     
  18. Streit M, Hemberger M, Häfner S, Knote F, Langenhan T, Beliu G (2023). Optimized genetic code expansion technology for time-dependent induction of adhesion GPCR-ligand engagement. Protein Sci, 32, 4614.
     
  19. Baalmann F, Brendler J, Butthof A, Popkova Y, Engel KM, Schiller J, Winter K, Lede V, Ricken A, Schöneberg T, Schulz A (2023). Reduced urine volume and changed renal sphingolipid metabolism in P2ry14-deficient mice. Front Cell Dev Biol, 11, 1128456.
     
  20. Wilde C, Chaudhry PM, Luo R, Simon KU, Piao X, Liebscher I (2023). Collagen VI Is a Gi-Biased Ligand of the Adhesion GPCR GPR126/ADGRG6. Cells, 12, 1551.
     
  21. Kuhn CK, Meister J, Kreft S, Stiller M, Puppel SH, Zaremba A, Scheffler B, Ullrich V, Schöneberg T, Schadendorf D, Horn S (2023). TERT expression is associated with metastasis from thin primaries, exhausted CD4+ T cells in melanoma and with DNA repair across cancer entities. PLoS One, 18, e0281487.
     
  22. Seufert F, Chung YK, Hildebrand PW, Langenhan T (2023). 7TM domain structures of adhesion GPCRs: what's new and what's missing? Trends Biochem Sci, 48, 726-739.
     
  23. Boeschen M, Le Duc D, Stiller M, von Laffert M, Schöneberg T, Horn S (2023). Interactive webtool for analyzing drug sensitivity and resistance associated with genetic signatures of cancer cell lines. J Cancer Res Clin Oncol, 149, 5539-5545.
     
  24. Mrestani A, Dannhäuser S, Pauli M, Kollmannsberger P, Hübsch M, Morris L, Langenhan T, Heckmann M, Paul MM (2023). Nanoscaled RIM clustering at presynaptic active zones revealed by endogenous tagging. Life Sci Alliance, 6, e202302021.
     
  25. Kaczmarek I, Wower I, Ettig K, Kuhn CK, Kraft R, Landgraf K, Körner A, Schöneberg T, Horn S, Thor D (2023). Identifying G protein-coupled receptors involved in adipose tissue function using the innovative RNA-seq database FATTLAS. iScience, 26, 107841.
     
  26. Kleinau G, Ali AH, Wiechert F, Szczepek M, Schmidt A, Spahn CMT, Liebscher I, Schöneberg T, Scheerer P (2023). Intramolecular activity regulation of adhesion GPCRs in light of recent structural and evolutionary information. Pharmacol Res, 197, 106971.
     
  27. Kieslich B, Weiße RH, Brendler J, Ricken A, Schöneberg T, Sträter N (2023). The dimerized pentraxin-like domain of the adhesion G protein-coupled receptor 112 (ADGRG4) suggests function in sensing mechanical forces. J Biol Chem, 299(12), 105356.
     
  28. Langenhan T (2023). Adhesion GPCRs in glioblastoma revisited. Cell Rep, 42, 113474.
     
  29. Schildbach VAS, Horn S, Hidalgo-Gadea G, Johannis W, Mauch C, Franklin C (2023). C-Reactive Protein and Lymphocyte-to-Monocyte Ratio Predict Recurrence in Stage III Melanoma Patients with Microscopic Sentinel Lymph Node Metastasis. Cancers (Basel), 15, 702.
     
  30. Entsie P, Kang Y, Amoafo EB, Schöneberg T, Liverani E (2023). The Signaling Pathway of the ADP Receptor P2Y(12) in the Immune System: Recent Discoveries and New Challenges. Int J Mol Sci, 24, 6709.
     
  31. Franklin C, Mohr P, Bluhm L, Meier F, Garzarolli M, Weichenthal M, Kähler K, Grimmelmann I, Gutzmer R, Utikal J, Terheyden P, Herbst R, Haferkamp S, Pfoehler C, Forschner A, Leiter U, Ziller F, Meiss F, Ulrich J, Kreuter A, Gebhardt C, Welzel J, Schilling B, Kaatz M, Scharfetter-Kochanek K, Dippel E, Nashan D, Sachse M, Weishaupt C, Löffler H, Gambichler T, Loquai C, Heinzerling L, Grabbe S, Debus D, Schley G, Hassel JC, Weyandt G, Trommer M, Lodde G, Placke JM, Zimmer L, Livingstone E, Becker J (2023). Brain metastasis and survival outcomes after first-line therapy in metastatic melanoma: a multicenter DeCOG study on 1704 patients from the prospective skin cancer registry ADOREG. J Immunother Cancer, 11, 005828.
     
  32. Thane M, Paisios E, Stöter T, Krüger AR, Gläß S, Dahse AK, Scholz N, Gerber B, Lehmann DJ, Schleyer M (2023). High-resolution analysis of individual Drosophila melanogaster larvae uncovers individual variability in locomotion and its neurogenetic modulation. Open Biol, 13, 220308.
     
  33. Jusyte M, Blaum N, Böhme MA, Berns MMM, Bonard AE, Vámosi ÁB, Pushpalatha KV, Kobbersmed JRL, Walter AM (2023). Unc13A dynamically stabilizes vesicle priming at synaptic release sites for short-term facilitation and homeostatic potentiation. Cell Rep, 42, 112541.
     
  34. Bundalian L, Su YY, Chen S, Velluva A, Kirstein AS, Garten A, Biskup S, Battke F, Lal D, Heyne HO, Platzer K, Lin CC, Lemke JR, Le Duc D (2023). Epilepsies of presumed genetic etiology show enrichment of rare variants that occur in the general population. Am J Hum Genet, 110, 1110-1122.
     
  35. Frenster JD, Erdjument-Bromage H, Stephan G, Ravn-Boess N, Wang S, Liu W, Bready D, Wilcox J, Kieslich B, Jankovic M, Wilde C, Horn S, Sträter N, Liebscher I, Schöneberg T, Fenyo D, Neubert TA, Placantonakis DG (2023). PTK7 is a positive allosteric modulator of GPR133 signaling in glioblastoma. Cell Rep, 42, 112679.
     
  36. Boeschen M, Kuhn CK, Wirtz H, Seyfarth HJ, Frille A, Lordick F, Hacker UT, Obeck U, Stiller M, Bläker H, von Laffert M (2023). Comparative bioinformatic analysis of KRAS, STK11 and KEAP1 (co-)mutations in non-small cell lung cancer with a special focus on KRAS G12C. Lung Cancer, 184, 107361.
     
  37. Stupia S, Heeke C, Brüggemann A, Zaremba A, Thier B, Kretz J, Sucker A, Philip M, Zelinskyy G, Ferrone S, Roesch A, Horn S, Hadaschik E, Schadendorf D, Trilling M, Dittmer U, Griewank K, Zhao F, Paschen A (2023). HLA Class II Loss and JAK1/2 Deficiency Coevolve in Melanoma Leading to CD4 T-cell and IFN? Cross-Resistance. Clin Cancer Res, 29, 2894-2907.
     
  38. Buchenauer L, Haange SB, Bauer M, Rolle-Kampczyk UE, Wagner M, Stucke J, Elter E, Fink B, Vass M, von Bergen M, Schulz A, Zenclussen AC, Junge KM, Stangl GI, Polte T (2023). Maternal exposure of mice to glyphosate induces depression- and anxiety-like behavior in the offspring via alterations of the gut-brain axis. Sci Total Environ, 905, 167034.
     
  39. Váraljai R, Zimmer L, Al-Matary Y, Kaptein P, Albrecht LJ, Shannan B, Brase JC, Gusenleitner D, Amaral T, Wyss N, Utikal J, Flatz L, Rambow F, Reinhardt HC, Dick J, Engel DR, Horn S, Ugurel S, Sondermann W, Livingstone E, Sucker A, Paschen A, Zhao F, Placke JM, Klose JM, Fendler WP, Thommen DS, Helfrich I, Schadendorf D, Roesch A (2023). Interleukin 17 signaling supports clinical benefit of dual CTLA-4 and PD-1 checkpoint inhibition in melanoma. Nat Cancer, 4, 1292-1308.
     
  40. Fu C, Huang W, Tang Q, Niu M, Guo S, Langenhan T, Song G, Yan J (2023). Unveiling Mechanical Activation: GAIN Domain Unfolding and Dissociation in Adhesion GPCRs. Nano Lett, 23, 9179-9186.
     
  41. Breitfeld J, Horn K, Le Duc D, Velluva A, Marzi C, Grallert H, Friedrich N, Pietzner M, Völker U, Völzke H, Ahlqvist E, Aly DM, Tuomi T, Baber R, Kratzsch J, Thiery J, Isermann B, Loeffler M, Klöting N, Blüher M, Stumvoll M, Heiker JT, Tönjes A, Scholz M, Kovacs P (2023). Genetic dissection of serum vaspin highlights its causal role in lipid metabolism. Obesity (Silver Spring), 31, 2862-2874.
     
  42. Strutt H, Warrington S, Madathil ACK, Langenhan T, Strutt D (2023). Molecular symmetry breaking in the Frizzled-dependent planar polarity pathway. Curr Biol, 33, 5340-5354.
     
  43. Alexander SPH, Christopoulos A, Davenport AP, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA, Abbracchio MP, Abraham G, Agoulnik A, Alexander W, Al-Hosaini K, Bäck M, Baker JG, Barnes NM, Bathgate R, Beaulieu JM, Beck-Sickinger AG, Behrens M, Bernstein KE, Bettler B, Birdsall NJM, Blaho V, Boulay F, Bousquet C, Bräuner-Osborne H, Burnstock G, Caló G, Castaño JP, Catt KJ, Ceruti S, Chazot P, Chiang N, Chini B, Chun J, Cianciulli A, Civelli O, Clapp LH, Co (2023). The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors. Br J Pharmacol, 180, 23-144.
     
  44. Pillaiyar T, Wozniak M, Abboud D, Rasch A, Liebing AD, Poso A, Kronenberger T, Stäubert C, Laufer SA, Hanson J (2023). Development of Ligands for the Super Conserved Orphan G Protein-Coupled Receptor GPR27 with Improved Efficacy and Potency. J Med Chem, 66, 17118-17137.
     
  45. Lin F, Tang R, Zhang C, Scholz N, Nagel G, Gao S (2023). Combining different ion-selective channelrhodopsins to control water flux by light. Pflugers Arch, 475, 1375-1385.
     
  46. Nel I, Münch C, Shamkeeva S, Heinemann ML, Isermann B, Aktas B (2023). The Challenge to Stabilize, Extract and Analyze Urinary Cell-Free DNA (ucfDNA) during Clinical Routine. Diagnostics (Basel), 13, 3670.
     


    47. 2022


  47. Kaczmarek I, Suchý T, Prömel S, Schöneberg T, Liebscher I, Thor D (2022). The relevance of adhesion G protein-coupled receptors in metabolic functions. Biol Chem, 403, 195-209.
     
  48. Kaczmarek I, Suchý T, Prömel S, Schöneberg T, Liebscher I, Thor D (2022). The relevance of adhesion G protein-coupled receptors in metabolic functions. Biol Chem, 403, 195-209.
     
  49. Kaczmarek I, Suchý T, Prömel S, Schöneberg T, Liebscher I, Thor D (2022). The relevance of adhesion G protein-coupled receptors in metabolic functions. Biol Chem, 403, 195-209.
     
  50. Le Duc D, Velluva A, Cassatt-Johnstone M, Olsen RA, Baleka S, Lin CC, Lemke JR, Southon JR, Burdin A, Wang MS, Grunewald S, Rosendahl W, Joger U, Rutschmann S, Hildebrandt TB, Fritsch G, Estes JA, Kelso J, Dalén L, Hofreiter M, Shapiro B, Schöneberg T (2022). Genomic basis for skin phenotype and cold adaptation in the extinct Steller's sea cow. Sci Adv, 8, eabl6496.
     
  51. Groß VE, Gershkovich MM, Schöneberg T, Kaiser A, Prömel S (2022). NanoBRET in C. elegans illuminates functional receptor interactions in real time. BMC Mol Cell Biol, 23, 8.
     
  52. Götze KJ, Mrestani A, Beckmann P, Krohn K, Le Duc D, Velluva A, Böhme MA, Heckmann M, Abou Jamra R, Lemke JR, Bläker H, Scholz N, Ljaschenko D, Langenhan T (2022). Improving one-step scarless genome editing in Drosophila melanogaster by combining ovoD co-CRISPR selection with sgRNA target site masking. Biol Methods Protoc, 7, bpac003.
     
  53. Korobeynikov VA, Lyashchenko AK, Blanco-Redondo B, Jafar-Nejad P, Shneider NA (2022). Antisense oligonucleotide silencing of FUS expression as a therapeutic approach in amyotrophic lateral sclerosis. Nat Med, 28, 104-116.
     
  54. Peters A, Rabe P, Liebing AD, Krumbholz P, Nordström A, Jäger E, Kraft R, Stäubert C (2022). Hydroxycarboxylic acid receptor 3 and GPR84 - Two metabolite-sensing G protein-coupled receptors with opposing functions in innate immune cells. Pharmacol Res, 176, 106047.
     
  55. Matú? D, Post WB, Horn S, Schöneberg T, Prömel S (2022). Latrophilin-1 drives neuron morphogenesis and shapes chemo- and mechanosensation-dependent behavior in C. elegans via a trans function. Biochem Biophys Res Commun, 589, 152-158.
     
  56. Rabe P, Liebing AD, Krumbholz P, Kraft R, Stäubert C (2022). Succinate receptor 1 inhibits mitochondrial respiration in cancer cells addicted to glutamine. Cancer Lett, 526, 91-102.
     
  57. Thor D (2022). G protein-coupled receptors as regulators of pancreatic islet functionality. Biochim Biophys Acta Mol Cell Res, 1869, 119235.
     
  58. Häfner S, Sandoz G (2022). Photopharmacological approaches for dissecting potassium channel physiology. Curr Opin Pharmacol, 63, 102178.
     
  59. Zimmermann A, Vu O, Brüser A, Sliwoski G, Marnett LJ, Meiler J, Schöneberg T (2022). Mapping the Binding Sites of UDP and Prostaglandin E2 Glyceryl Ester in the Nucleotide Receptor P2Y6. ChemMedChem, 17, e202100683.
     
  60. Ping YQ, Xiao P, Yang F, Zhao RJ, Guo SC, Yan X, Wu X, Zhang C, Lu Y, Zhao F, Zhou F, Xi YT, Yin W, Liu FZ, He DF, Zhang DL, Zhu ZL, Jiang Y, Du L, Feng SQ, Schöneberg T, Liebscher I, Xu HE, Sun JP (2022). Structural basis for the tethered peptide activation of adhesion GPCRs. Nature, 604, 763-770.
     
  61. Wilde C, Mitgau J, Suchý T, Schöneberg T, Liebscher I (2022). Translating the force-mechano-sensing GPCRs. Am J Physiol Cell Physiol, 322, C1047-C1060.
     
  62. Ott F, Körner C, Werner K, Gericke M, Liebscher I, Lobsien D, Radrezza S, Shevchenko A, Hofmann U, Kratzsch J, Gebhardt R, Berg T, Matz-Soja M (2022). Hepatic Hedgehog Signaling Participates in the Crosstalk between Liver and Adipose Tissue in Mice by Regulating FGF21. Cells, 11, 1680.
     
  63. Rabe P, Gehmlich M, Peters A, Krumbholz P, Nordström A, Stäubert C (2022). Combining metabolic phenotype determination with metabolomics and transcriptional analyses to reveal pathways regulated by hydroxycarboxylic acid receptor 2. Discov Oncol, 13, 47.
     
  64. Liebscher I, Schöneberg T, Thor D (2022). Stachel-mediated activation of adhesion G protein-coupled receptors: insights from cryo-EM studies Signal Transduct Target Ther, 7, 227.
     
  65. Mitgau J, Franke J, Schinner C, Stephan G, Berndt S, Placantonakis DG, Kalwa H, Spindler V, Wilde C, Liebscher I (2022). The N Terminus of Adhesion G Protein-Coupled Receptor GPR126/ADGRG6 as Allosteric Force Integrator. Front Cell Dev Biol, 10, 873278.
     
  66. Körner MB, Velluva A, Bundalian L, Radtke M, Lin CC, Zacher P, Bartolomaeus T, Kirstein AS, Mrestani A, Scholz N, Platzer K, Teichmann AC, Hentschel J, Langenhan T, Lemke JR, Garten A, Abou Jamra R, Le Duc D (2022). Altered gene expression profiles impair the nervous system development in individuals with 15q13.3 microdeletion. Sci Rep., 12, 13507.
     
  67. Schulze AS, Kleinau G, Krakowsky R, Rochmann D, Das R, Worth CL, Krumbholz P, Scheerer P, Stäubert C (2022). Evolutionary analyses reveal immune cell receptor GPR84 as a conserved receptor for bacteria-derived molecules. iScience, 25, 105087.
     
  68. Stäubert C, Wozniak M, Dupuis N, Laschet C, Pillaiyar T, Hanson J (2022). Superconserved receptors expressed in the brain: Expression, function, motifs and evolution of an orphan receptor family. Pharmacol Ther, 240, 108217.
     
  69. Paul MM, Dannhäuser S, Morris L, Mrestani A, Hübsch M, Gehring J, Hatzopoulos GN, Pauli M, Auger GM, Bornschein G, Scholz N, Ljaschenko D, Müller M, Sauer M, Schmidt H, Kittel RJ, DiAntonio A, Vakonakis I, Heckmann M, Langenhan T (2022). The human cognition-enhancing CORD7 mutation increases active zone number and synaptic release. Brain, 145, 3787-3802.
     
  70. Liebscher I, Cevhero?lu O, Hsiao CC, Maia AF, Schihada H, Scholz N, Soave M, Spiess K, Trajkovi? K, Kosloff M, Prömel S (2022). A guide to adhesion GPCR research. FEBS J, 289, 7610-7630.
     
  71. Dannhäuser S, Mrestani A, Gundelach F, Pauli M, Komma F, Kollmannsberger P, Sauer M, Heckmann M, Paul MM (2022). Endogenous tagging of Unc-13 reveals nanoscale reorganization at active zones during presynaptic homeostatic potentiation. Front Cell Neurosci, 16, 1074304.
     
  72. Knapp B, Roedig J, Roedig H, Krzysko J, Horn N, Güler BE, Kusuluri DK, Yildirim A, Boldt K, Ueffing M, Liebscher I, Wolfrum U (2022). Affinity Proteomics Identifies Interaction Partners and Defines Novel Insights into the Function of the Adhesion GPCR VLGR1/ADGRV1. Molecules, 27, 3108.
     
  73. Busche M, Rabl D, Fischer J, Schmees C, Mayr T, Gebhardt R, Stelzle M (2022). Continous, non-invasive monitoring of oxygen consumption in a parallelized microfluidic in vitro system provides novel insight into the response to nutrients and drugs of primary human hepatocytes. EXCLI J, 21, 144-161.
     
  74. Brendler J, Winter K, Lochhead P, Schulz A, Ricken AM (2022). Histological differences between lumbar and tail intervertebral discs in mice. J Anat, 240, 84-93.
     
  75. Junge KM, Buchenauer L, Strunz S, Seiwert B, Thürmann L, Rolle-Kampczyk UE, Röder S, Borte M, Kiess W, von Bergen M, Simon JC, Zenclussen AC, Schöneberg T, Stangl GI, Herberth G, Lehmann I, Reemtsma T, Polte T (2022). Effects of exposure to single and multiple parabens on asthma development in an experimental mouse model and a prospective cohort study. Sci Total Environ, 814, 152676.
     
  76. Franklin C, Mohr P, Bluhm L, Grimmelmann I, Gutzmer R, Meier F, Garzarolli M, Weichenthal M, Pfoehler C, Herbst R, Terheyden P, Utikal J, Ulrich J, Debus D, Haferkamp S, Kaatz M, Forschner A, Leiter U, Nashan D, Kreuter A, Sachse M, Welzel J, Heinzerling L, Meiss F, Weishaupt C, Gambichler T, Weyandt G, Dippel E, Schatton K, Celik E, Trommer M, Helfrich I, Roesch A, Zimmer L, Livingstone E, Schadendorf D, Horn S, Ugurel S (2022). Impact of radiotherapy and sequencing of systemic therapy on survival outcomes in melanoma patients with previously untreated brain metastasis: a multicenter DeCOG study on 450 patients from the prospective skin cancer registry ADOREG. J Immunother Cancer, 10, 1-15.
     
  77. Thier B, Zhao F, Stupia S, Brüggemann A, Koch J, Schulze N, Horn S, Coch C, Hartmann G, Sucker A, Schadendorf D, Paschen A (2022). Innate immune receptor signaling induces transient melanoma dedifferentiation while preserving immunogenicity. J Immunother Cancer, 10, 003863.
     
  78. Stephan G, Frenster JD, Liebscher I, Placantonakis DG (2022). Activation of the adhesion G protein-coupled receptor GPR133 by antibodies targeting its N-terminus. J Biol Chem, 298, 101949.
     
  79. Zaremba A, Jansen P, Murali R, Mayakonda A, Riedel A, Krahl D, Burkhardt H, John S, Géraud C, Philip M, Kretz J, Möller I, Stadtler N, Sucker A, Paschen A, Ugurel S, Zimmer L, Livingstone E, Horn S, Plass C, Schadendorf D, Hadaschik E, Lutsik P, Griewank K (2022). Genetic and Methylation Analysis of CTNNB1 in Benign and Malignant Melanocytic Lesions. Cancers (Basel), 14, 4066.
     
  80. Zaremba A, Jansen P, Murali R, Mayakonda A, Riedel A, Philip M, Rose C, Schaller J, Müller H, Kutzner H, Möller I, Stadtler N, Kretz J, Sucker A, Bankfalvi A, Livingstone E, Zimmer L, Horn S, Paschen A, Plass C, Schadendorf D, Hadaschik E, Lutsik P, Griewank K (2022). Genetic and methylation profiles distinguish benign, malignant and spitzoid melanocytic tumors. Int J Cancer, 151, 1542-1554.
     
  81. Olbrich A, Gros O, Ebel S, Denecke T, Gößmann H, Linder N, Lordick F, Forstmeyer D, Seehofer D, Sucher R, Rademacher S, Niemeyer J, Matz-Soja M, Berg T, Bömmel FV (2022). Dickkopf-Related Protein 1 as Response Marker for Transarterial Chemoembolization of Hepatocellular Carcinomas. Cancers (Basel), 14, 4807.
     
  82. Albrecht LJ, Höwner A, Griewank K, Lueong SS, von Neuhoff N, Horn PA, Sucker A, Paschen A, Livingstone E, Ugurel S, Zimmer L, Horn S, Siveke JT, Schadendorf D, Váraljai R, Roesch A (2022). Circulating cell-free messenger RNA enables non-invasive pan-tumour monitoring of melanoma therapy independent of the mutational genotype. Clin Transl Med, 12, 1090.
     
  83. Buettner JM, Sowoidnich L, Gerstner F, Blanco-Redondo B, Hallermann S, Simon CM (2022). p53-dependent c-Fos expression is a marker but not executor for motor neuron death in spinal muscular atrophy mouse models. Front Cell Neurosci, 16, 1038276.
     
  84. Kempf E, Landgraf K, Stein R, Hanschkow M, Hilbert A, Abou Jamra R, Boczki P, Herberth G, Kühnapfel A, Tseng YH, Stäubert C, Schöneberg T, Kühnen P, Rayner NW, Zeggini E, Kiess W, Blüher M, Körner A (2022). Aberrant expression of agouti signaling protein (ASIP) as a cause of monogenic severe childhood obesity. Nat Metab, 4, 1697-1712.
     


    85. 2021


  85. Schöneberg T, Liebscher I (2021). Mutations in G Protein-Coupled Receptors: Mechanisms, Pathophysiology and Potential Therapeutic Approaches. Pharmacol Rev, 73, 89-119.
     
  86. Le Duc D, Lin CC, Popkova Y, Yang Z, Akhil V, Çakir MV, Grunewald S, Simon JC, Dietz A, Dannenberger D, Garten A, Lemke JR, Schiller J, Blüher M, Nono Nankam PA, Rolle-Kampczyk U, von Bergen M, Kelso J, Schöneberg T (2021). Reduced lipolysis in lipoma phenocopies lipid accumulation in obesity. Int J Obes (Lond), 45, 565-576.
     
  87. Váraljai R, Horn S, Sucker A, Piercianek D, Schmitt V, Carpinteiro A, Becker KA, Reifenberger J, Roesch A, Felsberg J, Reifenberger G, Sure U, Schadendorf D, Helfrich I (2021). Integrative Genomic Analyses of Patient-Matched Intracranial and Extracranial Metastases Reveal a Novel Brain-Specific Landscape of Genetic Variants in Driver Genes of Malignant Melanoma. Cancers (Basel), 13, 731.
     
  88. Beliu G, Altrichter S, Guixà-González R, Hemberger M, Brauer I, Dahse AK, Scholz N, Wieduwild R, Kuhlemann A, Batebi H, Seufert F, Pérez-Hernández G, Hildebrand PW, Sauer M, Langenhan T (2021). Tethered agonist exposure in intact adhesion/class B2 GPCRs through intrinsic structural flexibility of the GAIN domain. Mol Cell, 81, 905-921.e5.
     
  89. Berndt N, Kolbe E, Gajowski R, Eckstein J, Ott F, Meierhofer D, Holzhütter HG, Matz-Soja M (2021). Functional Consequences of Metabolic Zonation in Murine Livers: Insights for an Old Story. Hepatology, 73, 795-810.
     
  90. Hildebrandt N, Colditz J, Dutra C, Goes P, Salbach-Hirsch J, Thiele S, Hofbauer LC, Rauner M (2021). Role of osteogenic Dickkopf-1 in bone remodeling and bone healing in mice with type I diabetes mellitus. Sci Rep, 11, 1920.
     
  91. Berndt S, Liebscher I (2021). New Structural Perspectives in G Protein-Coupled Receptor-Mediated Src Family Kinase Activation. Int J Mol Sci, 22, 6489.
     
  92. Heydasch U, Kessler R, Warnke JP, Eschrich K, Scholz N, Bigl M (2021). Functional diversity of PFKFB3 splice variants in glioblastomas. PLoS One, 16, e0241092.
     
  93. Hochmuth L, Körner C, Ott F, Volke D, Cokan KB, Juvan P, Brosch M, Hofmann U, Hoffmann R, Rozman D, Berg T, Matz-Soja M (2021). Sex-dependent dynamics of metabolism in primary mouse hepatocytes. Arch Toxicol, 95, 3001-3013.
     
  94. Velluva A, Radtke M, Horn S, Popp B, Platzer K, Gjermeni E, Lin CC, Lemke JR, Garten A, Schöneberg T, Blüher M, Abou Jamra R, Le Duc D (2021). Phenotype-tissue expression and exploration (PTEE) resource facilitates the choice of tissue for RNA-seq-based clinical genetics studies BMC Genomics, 22, 802.
     
  95. Wittlake A, Primel S, Schöneberg T (2021). The Evolutionary History of Vertebrate Adhesion GPCRs and Its Implication on Their Classification Int J Mol Sci, 22, 11803.
     
  96. Rabe P, Liebing AD, Krumbholz P, Kraft R, Stäubert C (2021). Succinate receptor 1 inhibits mitochondrial respiration in cancer cells addicted to glutamine. Cancer Lett, 526, 91-102.
     
  97. Stenzel U, Horn S (2021). bathometer: lightning fast depth-of-reads query. Bioinformatics, 37, 4233–4234.
     
  98. Suchý T, Kaczmarek I, Maricic T, Zieschang C, Schöneberg T, Thor D, Liebscher I (2021). Evaluating the feasibility of Cas9 overexpression in 3T3-L1 cells for generation of genetic knock-out adipocyte cell lines. Adipocyte, 10, 631-645.
     
  99. Favara DM, Liebscher I, Jazayeri A, Nambiar M, Sheldon H, Banham AH, Harris AL (2021). Elevated expression of the adhesion GPCR ADGRL4/ELTD1 promotes endothelial sprouting angiogenesis without activating canonical GPCR signalling. Sci Rep, 11, 8870.
     
  100. Zaremba A, Lodde G, Murali R, Philip M, Cosgarea I, Jansen P, Chorti E, Rose C, Hemmerlein B, Matull J, Thielmann CM, Kretz J, Möller I, Sucker A, Paschen A, Livingstone E, Zimmer L, Horn S, Schadendorf D, Hadaschik E, Griewank K (2021). Molecular pathology as a diagnostic aid in difficult-to-classify melanocytic tumours with spitzoid morphology. Eur J Cancer, 148, 340-347.
     
  101. Smoli? T, Tav?ar P, Horvat A, ?erne U, Halu?an Vasle A, Tratnjek L, Kreft ME, Scholz N, Matis M, Petan T, Zorec R, Vardjan N (2021). Astrocytes in stress accumulate lipid droplets. Glia, 69(6), 1540-1562.
     
  102. Zimmermann A, Hänsel R, Gemünden K, Kegel-Hübner V, Babel J, Bläker H, Matz-Soja M, Seehofer D, Damm G (2021). In Vivo and In Vitro Characterization of Primary Human Liver Macrophages and Their Inflammatory State. Biomedicines, 9, 406.
     
  103. Georgiadi A, Lopez-Salazar V, Merahbi RE, Karikari RA, Ma X, Mourão A, Klepac K, Bühler L, Alfaro AJ, Kaczmarek I, Linford A, Bosma M, Shilkova O, Ritvos O, Nakamura N, Hirose S, Lassi M, Teperino R, Machado J, Scheideler M, Dietrich A, Geerlof A, Feuchtinger A, Blutke A, Fischer K, Müller TD, Kessler K, Schöneberg T, Thor D, Hornemann S, Kruse M, Nawroth P, Pivovarova-Ramich O, Pfeiffer AFH, Sattler M, Blüher M, Herzig S (2021). Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue. Nat Commun, 12, 2999.
     
  104. Thangapandi VR, Knittelfelder O, Brosch M, Patsenker E, Vvedenskaya O, Buch S, Hinz S, Hendricks A, Nati M, Herrmann A, Rekhade DR, Berg T, Matz-Soja M, Huse K, Klipp E, Pauling JK, Wodke JA, Miranda Ackerman J, Bonin MV, Aigner E, Datz C, von Schönfels W, Nehring S, Zeissig S, Röcken C, Dahl A, Chavakis T, Stickel F, Shevchenko A, Schafmayer C, Hampe J, Subramanian P (2021). Loss of hepatic Mboat7 leads to liver fibrosis. Gut, 70, 940-950.
     
  105. Gershkovich MM, Groß VE, Vu O, Schoeder CT, Meiler J, Prömel S, Kaiser A (2021). Structural Perspective on Ancient Neuropeptide Y-like System reveals Hallmark Features for Peptide Recognition and Receptor Activation. J Mol Biol, 433, 166992.
     
  106. Zaremba A, Philip M, Hassel JC, Glutsch V, Fiocco Z, Loquai C, Rafei-Shamsabadi D, Gutzmer R, Utikal J, Haferkamp S, Reinhardt L, Kähler KC, Weishaupt C, Moreira A, Thoms KM, Wilhelm T, Pföhler C, Roesch A, Ugurel S, Zimmer L, Stadtler N, Sucker A, Kiecker F, Heinzerling L, Meier F, Meiss F, Schlaak M, Schilling B, Horn S, Schadendorf D, Livingstone E (2021). Clinical characteristics and therapy response in unresectable melanoma patients stage IIIB-IIID with in-transit and satellite metastases. Eur J Cancer, 152, 139-154.
     
  107. Simon CM, Blanco-Redondo B, Buettner JM, Pagiazitis JG, Fletcher EV, Sime Longang JK, Mentis GZ (2021). Chronic Pharmacological Increase of Neuronal Activity Improves Sensory-Motor Dysfunction in Spinal Muscular Atrophy Mice. J Neurosci, 41, 376-389.
     
  108. Frenster JD, Stephan G, Ravn-Boess N, Bready D, Wilcox J, Kieslich B, Wilde C, Sträter N, Wiggin GR, Liebscher I, Schöneberg T, Placantonakis DG (2021). Functional impact of intramolecular cleavage and dissociation of adhesion G protein-coupled receptor GPR133 (ADGRD1) on canonical signaling. J Biol Chem, 296, 100798.
     
  109. Westbury MV, Le Duc D, Duchêne DA, Krishnan A, Prost S, Rutschmann S, Grau JH, Dalén L, Weyrich A, Norén K, Werdelin L, Dalerum F, Schöneberg T, Hofreiter M (2021). Ecological Specialization and Evolutionary Reticulation in Extant Hyaenidae. Mol Biol Evol, 38, 3884-3897.
     
  110. Alexander SP, Christopoulos A, Davenport AP, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Southan C, Davies JA, Abbracchio MP, Alexander W, Al-Hosaini K, Bäck M, Barnes NM, Bathgate R, Beaulieu JM, Bernstein KE, Bettler B, Birdsall NJM, Blaho V, Boulay F, Bousquet C, Bräuner-Osborne H, Burnstock G, Caló G, Castaño JP, Catt KJ, Ceruti S, Chazot P, Chiang N, Chini B, Chun J, Cianciulli A, Civelli O, Clapp LH, Couture R, Csaba Z, Dahlgren C, Dent G, Singh (2021). THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors. Br J Pharmacol, 178, 27-156.
     
  111. Buettner JM, Sime Longang JK, Gerstner F, Apel KS, Blanco-Redondo B, Sowoidnich L, Janzen E, Langenhan T, Wirth B, Simon CM (2021). Central synaptopathy is the most conserved feature of motor circuit pathology across spinal muscular atrophy mouse models. iScience, 24, 103376.
     
  112. Reiners N, Schnurra C, Trawinski H, Kannenberg J, Hermsdorf T, Aebischer A, Schöneberg T, Reiche S, Jassoy C (2021). Performance of a SARS CoV-2 antibody ELISA based on simultaneous measurement of antibodies against the viral nucleoprotein and receptor-binding domain. Eur J Clin Microbiol Infect Dis, 40(12), 2645-2649.
     


    113. 2020


  113. Peters A, Rabe P, Krumbholz P, Kalwa H, Kraft R, Schoneberg T, Staubert C (2020). Natural biased signaling of hydroxycarboxylic acid receptor 3 and G protein-coupled receptor 84. Cell Commun Signal, 18, 31.
     
  114. Rothe J, Kraft R, Schoneberg T, Thor D (2020). Exploring G Protein-Coupled Receptor Signaling in Primary Pancreatic Islets. Biol Proced Online, 22, 4.
     
  115. Spormann L, Rennert C, Kolbe E, Ott F, Lossius C, Lehmann R, Gebhardt R, Berg T, Matz-Soja M (2020). Cyclopamine and Rapamycin Synergistically Inhibit mTOR Signalling in Mouse Hepatocytes, Revealing an Interaction of Hedgehog and mTor Signalling in the Liver Cells, 8, E1817-1817.
     
  116. Suchý T, Zieschang C, Popkova Y, Kaczmarek I, Weiner J, Liebing AD, Çakir MV, Landgraf K, Gericke M, Pospisilik JA, Körner A, Heiker JT, Dannenberger D, Schiller J, Schöneberg T, Liebscher I, Thor D (2020). The repertoire of Adhesion G protein-coupled receptors in adipocytes and their functional relevance. Int J Obes (Lond), 44, 2124-2136.
     
  117. Schulze A, Kleinau G, Neumann S, Scheerer P, Schöneberg T, Brüser A (2020). The intramolecular agonist is obligate for activation of glycoprotein hormone receptors. FASEB J, 34, 11243–11256.
     
  118. Langenhan T (2020). Adhesion G protein-coupled receptors-Candidate metabotropic mechanosensors and novel drug targets. Basic Clin Pharmacol Toxicol, 126 Suppl 6, 5-16.
     
  119. Berndt N, Kolbe E, Gajowski R, Eckstein J, Ott F, Meierhofer D, Holzhütter HG, Matz-Soja M (2020). Functional Consequences of Metabolic Zonation in Murine Livers: Insights for an Old Story. Hepatology, 73(2), 795-810.
     
  120. Leppert B, Strunz S, Seiwert B, Schlittenbauer L, Schlichting R, Pfeiffer C, Roder S, Bauer M, Borte M, Stangl GI, Schoneberg T, Schulz A, Karkossa I, Rolle-Kampczyk UE, Thurmann L, von Bergen M, Escher BI, Junge KM, Reemtsma T, Lehmann I, Polte T (2020). Maternal paraben exposure triggers childhood overweight development. Nat Commun, 11, 561.
     
  121. Diaz-Aparicio I, Paris I, Sierra-Torre V, Plaza-Zabala A, Rodriguez-Iglesias N, Marquez-Ropero M, Beccari S, Huguet P, Abiega O, Alberdi E, Matute C, Bernales I, Schulz A, Otrokocsi L, Sperlagh B, Happonen KE, Lemke G, Maletic-Savatic M, Valero J, Sierra A (2020). Microglia Actively Remodel Adult Hippocampal Neurogenesis through the Phagocytosis Secretome. J Neurosci, 40, 1453-1482.
     
  122. Jacobson KA, Delicado EG, Gachet C, Kennedy C, von Kugelgen I, Li B, Miras-Portugal MT, Novak I, Schoneberg T, Perez-Sen R, Thor D, Wu B, Yang Z, Muller CE (2020). Update of P2Y receptor pharmacology: IUPHAR Review 27. Br J Pharmacol, 177, 2413-2433.
     
  123. Frenster JD, Kader M, Kamen S, Sun J, Chiriboga L, Serrano J, Bready D, Golub D, Ravn-Boess N, Stephan G, Chi AS, Kurz SC, Jain R, Park CY, Fenyo D, Liebscher I, Schöneberg T, Wiggin G, Newman R, Barnes M, Dickson JK, MacNeil DJ, Huang X, Shohdy N, Snuderl M, Zagzag D, Placantonakis DG (2020). Expression profiling of the adhesion G protein-coupled receptor GPR133 (ADGRD1) in glioma subtypes. Neurooncol Adv, 2, 053.
     
  124. Such L, Zhao F, Liu D, Thier B, Le-Trilling VTK, Sucker A, Coch C, Pieper N, Howe S, Bhat H, Kalkavan H, Ritter C, Brinkhaus R, Ugurel S, Köster J, Seifert U, Dittmer U, Schuler M, Lang KS, Kufer TA, Hartmann G, Becker JC, Horn S, Ferrone S, Liu D, Van Allen EM, Schadendorf D, Griewank K, Trilling M, Paschen A (2020). Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapy. J Clin Invest, 130, 4266-4281.
     
  125. Buniatian GH, Weiskirchen R, Weiss TS, Schwinghammer U, Fritz M, Seferyan T, Proksch B, Glaser M, Lourhmati A, Buadze M, Borkham-Kamphorst E, Gaunitz F, Gleiter CH, Lang T, Schaeffeler E, Tremmel R, Cynis H, Frey WH 2nd, Gebhardt R, Friedman SL, Mikulits W, Schwab M, Danielyan L (2020). Antifibrotic Effects of Amyloid-Beta and Its Loss in Cirrhotic Liver. Cells, 9(2), 452.
     
  126. Jäger E, Murthy S, Schmidt C, Hahn M, Strobel S, Peters A, Stäubert C, Sungur P, Venus T, Geisler M, Radusheva V, Raps S, Rothe K, Scholz R, Jung S, Wagner S, Pierer M, Seifert O, Chang W, Estrela-Lopis I, Raulien N, Krohn K, Sträter N, Hoeppener S, Schöneberg T, Rossol M, Wagner U (2020). Calcium-sensing receptor-mediated NLRP3 inflammasome response to calciprotein particles drives inflammation in rheumatoid arthritis. Nat Commun, 11, 4243.
     
  127. Busche M, Tomilova O, Schütte J, Werner S, Beer M, Groll N, Hagmeyer B, Pawlak M, Jones PD, Schmees C, Becker H, Schnabel J, Gall K, Hemmler R, Matz-Soja M, Damm G, Beuck S, Klaassen T, Moer J, Ullrich A, Runge D, Schenke-Layland K, Gebhardt R, Stelzle M (2020). HepaChip-MP - a twenty-four chamber microplate for a continuously perfused liver coculture model. Lab Chip, 20, 2911-2926.
     
  128. Wilpert NM, Krueger M, Opitz R, Sebinger D, Paisdzior S, Mages B, Schulz A, Spranger J, Wirth EK, Stachelscheid H, Mergenthaler P, Vajkoczy P, Krude H, Kühnen P, Bechmann I, Biebermann H (2020). Spatiotemporal Changes of Cerebral Monocarboxylate Transporter 8 Expression. Thyroid, 30, 1366-1383.
     
  129. Mathiasen S, Palmisano T, Perry NA, Stoveken HM, Vizurraga A, McEwen DP, Okashah N, Langenhan T, Inoue A, Lambert NA, Tall GG, Javitch JA (2020). G12/13 is activated by acute tethered agonist exposure in the adhesion GPCR ADGRL3. Nat Chem Biol, 16, 1343-1350.
     
  130. Dannhäuser S, Lux TJ, Hu C, Selcho M, Chen JT, Ehmann N, Sachidanandan D, Stopp S, Pauls D, Pawlak M, Langenhan T, Soba P, Rittner HL, Kittel RJ (2020). Antinociceptive modulation by the adhesion GPCR CIRL promotes mechanosensory signal discrimination. Elife, 9, 56738-56738.
     
  131. Cokan KB, Urlep ?, Lorbek G, Matz-Soja M, Skubic C, Per?e M, Jeruc J, Juvan P, Re?en T, Rozman D (2020). Chronic Disruption of the Late Cholesterol Synthesis Leads to Female-Prevalent Liver Cancer. Cancers (Basel), 12, 3302.
     
  132. Enigk K, Jentsch H, Rodloff AC, Eschrich K, Stingu CS (2020). Activity of five antimicrobial peptides against periodontal as well as non-periodontal pathogenic strains. J Oral Microbiol, 12, 1829405.
     
  133. Livingstone E, Zaremba A, Horn S, Ugurel S, Casalini B, Schlaak M, Hassel JC, Herbst R, Utikal JS, Weide B, Gutzmer R, Meier F, Koelsche C, Hadaschik E, Sucker A, Reis H, Merkelbach-Bruse S, Siewert M, Sahm F, von Deimling A, Cosgarea I, Zimmer L, Schadendorf D, Schilling B, Griewank KG (2020). GNAQ and GNA11 mutant nonuveal melanoma: a subtype distinct from both cutaneous and uveal melanoma. Br J Dermatol, 183, 928-939.
     
  134. Matz-Soja M (2020). Bile Acids as Regulatory Signalling Molecules. In: Rozman D, Gebhardt R , Mammalian Sterols: Novel Biological Roles of Cholesterol Synthesis Intermediates, Oxysterols and Bile Acids. (S. 101-116), Berlin: Springer Verlag.
     


    135. 2019


  135. Rothe J, Thor D, Winkler J, Knierim AB, Binder C, Huth S, Kraft R, Rothemund S, Schoneberg T, Promel S (2019). Involvement of the Adhesion GPCRs Latrophilins in the Regulation of Insulin Release. Cell Rep, 26, 1573-1584.
     
  136. Schöneberg T, Prömel S (2019). Latrophilins and Teneurins in Invertebrates: No Love for Each Other? Front Neurosci, 13, 154.
     
  137. Peters A, Krumbholz P, Jager E, Heintz-Buschart A, Cakir MV, Rothemund S, Gaudl A, Ceglarek U, Schoneberg T, Staubert C (2019). Metabolites of lactic acid bacteria present in fermented foods are highly potent agonists of human hydroxycarboxylic acid receptor 3. PLoS Genet, 15, e1008145.
     
  138. Scholz N, Ehmann N, Sachidanandan D, Imig C, Cooper BH, Jahn O, Reim K, Brose N, Meyer J, Lamberty M, Altrichter S, Bormann A, Hallermann S, Pauli M, Heckmann M, Stigloher C, Langenhan T, Kittel RJ (2019). Complexin cooperates with Bruchpilot to tether synaptic vesicles to the active zone cytomatrix. J Cell Biol, 218, 1011-1026.
     
  139. Marbach-Breitruck E, Matz-Soja M, Abraham U, Schmidt-Heck W, Sales S, Rennert C, Kern M, Aleithe S, Spormann L, Thiel C, Gerlini R, Arnold K, Kloting N, Guthke R, Rozman D, Teperino R, Shevchenko A, Kramer A, Gebhardt R (2019). Tick-tock hedgehog-mutual crosstalk with liver circadian clock promotes liver steatosis. J Hepatol, 70, 1192-1202.
     
  140. Knierim AB, Rothe J, Cakir MV, Lede V, Wilde C, Liebscher I, Thor D, Schoneberg T (2019). Genetic basis of functional variability in adhesion G protein-coupled receptors. Sci Rep, 9, 11036-11036.
     
  141. Heshof R, Visscher B, Promel S, Hughes S (2019). Large-scale cultivation of Caenorhabditis elegans in a bioreactor using a labor-friendly fed-batch approach. Biotechniques, 67, 33-39.
     
  142. Gershkovich MM, Gross VE, Kaiser A, Promel S (2019). Pharmacological and functional similarities of the human neuropeptide Y system in C. elegans challenges phylogenetic views on the FLP/NPR system. Cell Commun Signal, 17, 123.
     
  143. Kessler R, Fleischer M, Springsguth C, Bigl M, Warnke JP, Eschrich K (2019). Prognostic Value of PFKFB3 to PFKFB4 mRNA Ratio in Patients With Primary Glioblastoma (IDH-Wildtype). J Neuropathol Exp Neurol, 78, 865-870.
     
  144. Scholz N, Langenhan T, Schoneberg T (2019). Revisiting the classification of adhesion GPCRs. Ann N Y Acad Sci, 1456, 80-95.
     
  145. Eichler W, Lohrenz A, Simon KU, Krohn S, Lange J, Burger S, Liebscher I (2019). The role of ADGRE5/CD97 in human retinal pigment epithelial cell growth and survival. Ann N Y Acad Sci, 1456, 64-79.
     
  146. Blanco-Redondo B, Nuwal N, Kneitz S, Nuwal T, Halder P, Liu Y, Ehmann N, Scholz N, Mayer A, Kleber J, Kahne T, Schmitt D, Sadanandappa MK, Funk N, Albertova V, Helfrich-Forster C, Ramaswami M, Hasan G, Kittel RJ, Langenhan T, Gerber B, Buchner E (2019). Implications of the Sap47 null mutation for synapsin phosphorylation, longevity, climbing proficiency and behavioural plasticity in adult Drosophila. J Exp Biol, 222, 203505.
     
  147. Wieduwild R, Xu Y, Ostrovidov S, Khademhosseini A, Zhang Y, Orive G (2019). Engineering Hydrogels beyond a Hydrated Network. Adv Healthc Mater, 8, e1900038.
     
  148. Kolbe E, Aleithe S, Rennert C, Spormann L, Ott F, Meierhofer D, Gajowski R, Stopel C, Hoehme S, Kucken M, Brusch L, Seifert M, von Schoenfels W, Schafmayer C, Brosch M, Hofmann U, Damm G, Seehofer D, Hampe J, Gebhardt R, Matz-Soja M (2019). Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and Human. Cell Rep, 29(13), 4553-4567.e7.
     
  149. Wach S, Brandl M, Borchardt H, Weigelt K, Lukat S, Nolte E, Al-Janabi O, Hart M, Grasser F, Giedl J, Jung R, Stohr R, Hartmann A, Lieb V, Hobel S, Peters A, Staubert C, Wullich B, Taubert H, Aigner A (2019). Exploring the MIR143-UPAR Axis for the Inhibition of Human Prostate Cancer Cells In Vitro and In Vivo. Mol Ther Nucleic Acids, 16, 272-283.
     
  150. Min Q, Molina L, Li J, Adebayo Michael AO, Russell JO, Preziosi ME, Singh S, Poddar M, Matz-Soja M, Ranganathan S, Bell AW, Gebhardt R, Gaunitz F, Yu J, Tao J, Monga SP (2019). ?-Catenin and Yes-Associated Protein 1 Cooperate in Hepatoblastoma Pathogenesis. Am J Pathol, 189, 1091-1104.
     
  151. Alexander SPH, Christopoulos A, Davenport AP, Kelly E, Mathie A, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA (2019). THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein-coupled receptors. Br J Pharmacol, 176, 21-141.
     
  152. Bradley EC, Cunningham RL, Wilde C, Morgan RK, Klug EA, Letcher SM, Schoneberg T, Monk KR, Liebscher I, Petersen SC (2019). In vivo identification of small molecules mediating Gpr126/Adgrg6 signaling during Schwann cell development. Ann N Y Acad Sci, 1456, 44-63.
     
  153. Morgan RK, Anderson GR, Arac D, Aust G, Balenga N, Boucard A, Bridges JP, Engel FB, Formstone CJ, Glitsch MD, Gray RS, Hall RA, Hsiao CC, Kim HY, Knierim AB, Kusuluri DK, Leon K, Liebscher I, Piao X, Promel S, Scholz N, Srivastava S, Thor D, Tolias KF, Ushkaryov YA, Vallon M, Van Meir EG, Vanhollebeke B, Wolfrum U, Wright KM, Monk KR, Mogha A (2019). The expanding functional roles and signaling mechanisms of adhesion G protein-coupled receptors. Ann N Y Acad Sci, 1456, 5-25.
     
  154. Ghallab A, Myllys M, Holland CH, Zaza A, Murad W, Hassan R, Ahmed YA, Abbas T, Abdelrahim EA, Schneider KM, Matz-Soja M, Reinders J, Gebhardt R, Berres ML, Hatting M, Drasdo D, Saez-Rodriguez J, Trautwein C, Hengstler JG (2019). Influence of Liver Fibrosis on Lobular Zonation. Cells, 8(12), 1556.
     
  155. Le Duc D, Schöneberg T (2019). Cellular Signalling Systems In: Brüne M, Schiefenhövel W, The Oxford Handbook of Evolutionary Medicine (S. 45-76), Oxford: Oxford University Press.
     
  156. Le Duc D, Schöneberg T (2019). Cellular Signalling Systems In: Brüne, M, Schiefenhövel W, Evolutionary Medicine (S. 45-76), Oxford: Oxford University Press.
     
  157. Matz-Soja M und andere (2019). Hedgehog Signaling and Liver Lipid Metabolism In: Vinood B. Patel, The Molecular Nutrition of Fats (S. 201-212), London, San Diego, Cambridge, Oxford: Academic Press, an imprint of Elsevier.
     


    158. 2018


  158. Schaumann R, Dallacker-Losensky K, Rosenkranz C, Genzel GH, Stingu CS, Schellenberger W, Schulz-Stubner S, Rodloff AC, Eschrich K (2018). Discrimination of Human Pathogen Clostridium Species Especially of the Heterogeneous C. sporogenes and C. botulinum by MALDI-TOF Mass Spectrometry. Curr Microbiol, 75(11), 1506-1515.
     
  159. Blanco-Redondo B, Langenhan T (2018). Parallel Genomic Engineering of Two Drosophila Genes Using Orthogonal attB/attP Sites. G3 (Bethesda), 8(9), 3109-3118.
     
  160. Matus D, Promel S (2018). G Proteins and GPCRs in C. elegans Development: A Story of Mutual Infidelity. J Dev Biol, 6, E28.
     
  161. Wieduwild R, Wetzel R, Husman D, Bauer S, El-Sayed I, Duin S, Murawala P, Thomas AK, Wobus M, Bornhauser M, Zhang Y (2018). Coacervation-Mediated Combinatorial Synthesis of Biomatrices for Stem Cell Culture and Directed Differentiation. Adv Mater, 30(22), e1706100-.
     
  162. Wieduwild R, Howarth M (2018). Assembling and decorating hyaluronan hydrogels with twin protein superglues to mimic cell-cell interactions. Biomaterials, 180, 253-264.
     
  163. Scholz N (2018). Cancer Cell Mechanics: Adhesion G Protein-coupled Receptors in Action? Front Oncol, 8, 59.
     
  164. Kurz S, Thieme R, Amberg R, Groth M, Jahnke HG, Pieroh P, Horn LC, Kolb M, Huse K, Platzer M, Volke D, Dehghani F, Buzdin A, Engel K, Robitzki A, Hoffmann R, Gockel I, Birkenmeier G (2018). Correction: The anti-tumorigenic activity of A2M-A lesson from the naked mole-rat. PLoS One, 13(3), 0195169.
     
  165. Schoneberg T, Meister J, Knierim AB, Schulz A (2018). The G protein-coupled receptor GPR34 - The past 20?years of a grownup. Pharmacol Ther, 189, 71-88.
     
  166. Rennert C, Vlaic S, Marbach-Breitruck E, Thiel C, Sales S, Shevchenko A, Gebhardt R, Matz-Soja M (2018). The Diurnal Timing of Starvation Differently Impacts Murine Hepatic Gene Expression and Lipid Metabolism - A Systems Biology Analysis Using Self-Organizing Maps. Front Physiol, 9, 1180-1180.
     
  167. Nazarko O, Kibrom A, Winkler J, Leon K, Stoveken H, Salzman G, Merdas K, Lu Y, Narkhede P, Tall G, Promel S, Arac D (2018). A Comprehensive Mutagenesis Screen of the Adhesion GPCR Latrophilin-1/ADGRL1. iScience, 3, 264-278.
     
  168. Thomas AK, Wieduwild R, Zimmermann R, Lin W, Friedrichs J, Bickle M, Fahmy K, Werner C, Zhang Y (2018). Layer-by-Layer Assembly of Heparin and Peptide-Polyethylene Glycol Conjugates to Form Hybrid Nanothin Films of Biomatrices. ACS Appl Mater Interfaces, 10(17), 14264-14270.
     
  169. Cohen H, Barash H, Meivar-Levy I, Molakandov K, Ben-Shimon M, Gurevich M, Zoabi F, Har-Zahav A, Gebhardt R, Gaunitz F, Gurevich M, Mor E, Ravassard P, Greenberger S, Ferber S (2018). The Wnt/?-catenin pathway determines the predisposition and efficiency of liver-to-pancreas reprogramming. Hepatology, 68(4), 1589-1603.
     
  170. Pieroh P, Wagner DC, Alessandri B, Dabbagh Nazari M, Ehrlich A, Ghadban C, Hobusch C, Birkenmeier G, Dehghani F (2018). Comparative Examination of Temporal Glyoxalase 1 Variations Following Perforant Pathway Transection, Excitotoxicity, and Controlled Cortical Impact Injury. Neurotox Res, 33(2), 412-421.
     
  171. Erdem B, Schulz A, Saglar E, Deniz F, Schoneberg T, Mergen H (2018). Functional characterization of AVPR2 mutants found in Turkish patients with nephrogenic diabetes insipidus. Endocr Connect, 7, 56-64.
     
  172. Hilbig D, Sittig D, Hoffmann F, Rothemund S, Warmt E, Quaas M, Sturmer J, Seiler L, Liebscher I, Hoang NA, Kas JA, Banks L, Aust G (2018). Mechano-Dependent Phosphorylation of the PDZ-Binding Motif of CD97/ADGRE5 Modulates Cellular Detachment. Cell Rep, 24(8), 1986-1995.
     
  173. Khajavi N, Finan B, Kluth O, Muller TD, Mergler S, Schulz A, Kleinau G, Scheerer P, Schurmann A, Gudermann T, Tschop MH, Krude H, DiMarchi RD, Biebermann H (2018). An incretin-based tri-agonist promotes superior insulin secretion from murine pancreatic islets via PLC activation. Cell Signal, 51, 13-22.
     
  174. Junge KM, Leppert B, Jahreis S, Wissenbach DK, Feltens R, Grutzmann K, Thurmann L, Bauer T, Ishaque N, Schick M, Bewerunge-Hudler M, Roder S, Bauer M, Schulz A, Borte M, Landgraf K, Korner A, Kiess W, (2018). MEST mediates the impact of prenatal bisphenol A exposure on long-term body weight development. Clin Epigenetics, 10, 58-.
     
  175. Brosch M, Kattler K, Herrmann A, von Schonfels W, Nordstrom K, Seehofer D, Damm G, Becker T, Zeissig S, Nehring S, Reichel F, Moser V, Thangapandi RV, Stickel F, Baretton G, Rocken C, Muders M, Matz-S (2018). Epigenomic map of human liver reveals principles of zonated morphogenic and metabolic control. Nat Commun, 9(1), 4150-4150.
     
  176. Dall M, Penke M, Sulek K, Matz-Soja M, Holst B, Garten A, Kiess W, Treebak JT (2018). Hepatic NAD+ levels and NAMPT abundance are unaffected during prolonged high-fat diet consumption in C57BL/6JBomTac mice. Mol Cell Endocrinol, 473, 245-256.
     
  177. Hsiao CC, Chu TY, Wu CJ, van den Biggelaar M, Pabst C, Hebert J, Kuijpers TW, Scicluna BP, I KY, Chen TC, Liebscher I, Hamann J, Lin HH (2018). The Adhesion G Protein-Coupled Receptor GPR97/ADGRG3 Is Expressed in Human Granulocytes and Triggers Antimicrobial Effector Functions. Front Immunol, 9, 2830.
     


    178. 2017


  178. Lede V, Meusel A, Garten A, Popkova Y, Penke M, Franke C, Ricken A, Schulz A, Kiess W, Huster D, Schoneberg T, Schiller J (2017). Altered hepatic lipid metabolism in mice lacking both the melanocortin type 4 receptor and low density lipoprotein receptor. PLoS One, 12(2), e0172000.
     
  179. Demberg LM, Winkler J, Wilde C, Simon KU, Schon J, Rothemund S, Schoneberg T, Promel S, Liebscher I (2017). Activation of Adhesion G Protein-coupled Receptors: AGONIST SPECIFICITY OF STACHEL SEQUENCE-DERIVED PEPTIDES. J Biol Chem, 292(11), 4383-4394.
     
  180. Alwahsh SM, Gebhardt R (2017). Dietary fructose as a risk factor for non-alcoholic fatty liver disease (NAFLD). Arch Toxicol, 91(4), 1545-1563.
     
  181. Bruser A, Zimmermann A, Crews BC, Sliwoski G, Meiler J, Konig GM, Kostenis E, Lede V, Marnett LJ, Schoneberg T (2017). Prostaglandin E2 glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y6. Sci Rep, 7(1), 2380.
     
  182. Kolb M, Kurz S, Schafer A, Huse K, Dietz A, Wichmann G, Birkenmeier G (2017). Verification and characterization of an alternative low density lipoprotein receptor-related protein 1 splice variant. PLoS One, 12(6), e0180354.
     
  183. Altrichter S, Haase M, Loh B, Kuhn A, Leptihn S (2017). Mechanism of the Spontaneous and Directional Membrane Insertion of a 2-Transmembrane Ion Channel. ACS Chem Biol, 12(2), 380-388.
     
  184. Matz-Soja M (2017). Computational modelling of Hedgehog signalling in liver Regeneration. Drug Discov Today: Disease Models, 22, 45-50.
     
  185. Scholz N, Guan C, Nieberler M, Grotemeyer A, Maiellaro I, Gao S, Beck S, Pawlak M, Sauer M, Asan E, Rothemund S, Winkler J, Promel S, Nagel G, Langenhan T, Kittel RJ (2017). Mechano-dependent signaling by Latrophilin/CIRL quenches cAMP in proprioceptive neurons. Elife, 6, 28360.
     
  186. Le Duc D, Schulz A, Lede V, Schulze A, Thor D, Bruser A, Schoneberg T (2017). P2Y Receptors in Immune Response and Inflammation. Adv Immunol, 136, 85-121.
     
  187. Debebe T, Biagi E, Soverini M, Holtze S, Hildebrandt TB, Birkemeyer C, Wyohannis D, Lemma A, Brigidi P, Savkovic V, Konig B, Candela M, Birkenmeier G (2017). Unraveling the gut microbiome of the long-lived naked mole-rat. Sci Rep, 7(1), 9590.
     
  188. Rennert C, Eplinius F, Hofmann U, Johanning J, Rolfs F, Schmidt-Heck W, Guthke R, Gebhardt R, Ricken AM, Matz-Soja M (2017). Conditional loss of hepatocellular Hedgehog signaling in female mice leads to the persistence of hepatic steroidogenesis, androgenization and infertility. Arch Toxicol, 91(11), 3677-3687.
     
  189. Stäubert C, Schöneberg T (2017). GPCR Signaling From Intracellular Membranes - A Novel Concept. Bioessays, 39(12), 200.
     
  190. Kurz S, Thieme R, Amberg R, Groth M, Jahnke HG, Pieroh P, Horn LC, Kolb M, Huse K, Platzer M, Volke D, Dehghani F, Buzdin A, Engel K, Robitzki A, Hoffmann R, Gockel I, Birkenmeier G (2017). The anti-tumorigenic activity of A2M-A lesson from the naked mole-rat. PLoS One, 12(12), e0189514.
     
  191. Piotrowski C, Lede V, Butthof A, Kaiser N, Hirrlinger PG, Tschop MH, Schoneberg T, Bechmann I (2017). Open housing drives the expression of immune response genes in the nasal mucosa, but not the olfactory bulb. PLoS One, 12, e0187192.
     
  192. Wewering F, Jouy F, Wissenbach DK, Gebauer S, Bluher M, Gebhardt R, Pirow R, von Bergen M, Kalkhof S, Luch A, Zellmer S (2017). Characterization of chemical-induced sterile inflammation in vitro: application of the model compound ketoconazole in a human hepatic co-culture system. Arch Toxicol, 91(2), 799-810.
     
  193. Merkwitz C, Blaschuk O, Winkler J, Schulz A, Promel S, Ricken AM (2017). Advantages and Limitations of Salmon-Gal/Tetrazolium Salt Histochemistry for the Detection of LacZ Reporter Gene Activity in Murine Epithelial Tissue. J Histochem Cytochem, 65(4), 197-206.
     
  194. Urlep Z, Lorbek G, Perse M, Jeruc J, Juvan P, Matz-Soja M, Gebhardt R, Bjorkhem I, Hall JA, Bonneau R, Littman DR, Rozman D (2017). Disrupting Hepatocyte Cyp51 from Cholesterol Synthesis Leads to Progressive Liver Injury in the Developing Mouse and Decreases RORC Signalling. Sci Rep, 7, 40775.
     
  195. Braune J, Weyer U, Matz-Soja M, Hobusch C, Kern M, Kunath A, Kloting N, Kralisch S, Bluher M, Gebhardt R, Zavros Y, Bechmann I, Gericke M (2017). Hedgehog signalling in myeloid cells impacts on body weight, adipose tissue inflammation and glucose metabolism. Diabetologia, 60(5), 889-899.
     
  196. Windholz J, Kovacs P, Schlicke M, Franke C, Mahajan A, Morris AP, Lemke JR, Klammt J, Kiess W, Schoneberg T, Pfaffle R, Korner A (2017). Copy number variations in "classical" obesity candidate genes are not frequently associated with severe early-onset obesity in children. J Pediatr Endocrinol Metab, 30(5), 507-515.
     
  197. Stingu CS, Eschrich K, Thiel J, Borgmann T, Schaumann R, Rodloff AC (2017). Identification of viridans streptococci With Matrix-Assisted Laser Desorption & Ionization Time-of-flight Mass Spectrometry by an In-house Method and a Commercially Available System. Ann Lab Med, 37(5), 434-437.
     
  198. Weigand K, Tischler-David U, Gebhardt R, Steisslinger HW, Matz-Soja M, Schmidt KH (2017). Feedback Inhibition of apolipoprotein A-I Synthesis by ist propeptide in hepatocyte cell culture and in the cell-free System. Journal of Hepatology and Gastroenterology, 2(3), 12-17.
     
  199. Lin HH, Hsiao CC, Pabst C, Hebert J, Schoneberg T, Hamann J (2017). Adhesion GPCRs in Regulating Immune Responses and Inflammation. Adv Immunol, 136, 163-201.
     
  200. Pieroh P, Wagner DC, Ghadban C, Birkenmeier G, Dehghani F (2017). Ethyl pyruvate does not require microglia for mediating neuroprotection after excitotoxic injury. CNS Neurosci Ther, 23(10), 798-807.
     
  201. Penke M, Schuster S, Gorski T, Gebhardt R, Kiess W, Garten A (2017). Oleate ameliorates palmitate-induced reduction of NAMPT activity and NAD levels in primary human hepatocytes and hepatocarcinoma cells. Lipids Health Dis, 16(1), 191.
     


    202. 2016


  202. Fischer L, Wilde C, Schoneberg T, Liebscher I (2016). Functional relevance of naturally occurring mutations in adhesion G protein-coupled receptor ADGRD1 (GPR133). BMC Genomics, 17, 609.
     
  203. Wilde C, Fischer L, Lede V, Kirchberger J, Rothemund S, Schoneberg T, Liebscher I (2016). The constitutive activity of the adhesion GPCR GPR114/ADGRG5 is mediated by its tethered agonist. FASEB J, 30, 666-673.
     
  204. Jager E, Schulz A, Lede V, Lin CC, Schoneberg T, Le Duc D (2016). Dendritic Cells Regulate GPR34 through Mitogenic Signals and Undergo Apoptosis in Its Absence. J Immunol, 196(6), 2504-2513.
     
  205. Schoneberg T, Kleinau G, Bruser A (2016). What are they waiting for?-Tethered agonism in G protein-coupled receptors. Pharmacol Res, 108, 9-15.
     
  206. Bruser A, Schulz A, Rothemund S, Ricken A, Calebiro D, Kleinau G, Schoneberg T (2016). The Activation Mechanism of Glycoprotein Hormone Receptors with Implications in the Cause and Therapy of Endocrine Diseases. J Biol Chem, 291(2), 508-520.
     
  207. Staubert C, Krakowsky R, Bhuiyan H, Witek B, Lindahl A, Broom O, Nordstrom A (2016). Increased lanosterol turnover: a metabolic burden for daunorubicin-resistant leukemia cells. Med Oncol, 33(1), 6.
     
  208. Matz-Soja M, Rennert C, Schonefeld K, Aleithe S, Boettger J, Schmidt-Heck W, Weiss TS, Hovhannisyan A, Zellmer S, Kloting N, Schulz A, Kratzsch J, Guthke R, Gebhardt R (2016). Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis. Elife, 5, e13308.
     
  209. Promel S, Fiedler F, Binder C, Winkler J, Schoneberg T, Thor D (2016). Deciphering and modulating G protein signalling in C. elegans using the DREADD technology. Sci Rep, 6, 28901.
     
  210. Le Duc D, Schoneberg T (2016). Adaptation to nocturnality - learning from avian genomes. Bioessays, 38(7), 694-703.
     
  211. Winkler J, Promel S (2016). The adhesion GPCR latrophilin - a novel signaling cascade in oriented cell division and anterior-posterior polarity. Worm, 5(2), e1170274.
     
  212. Birkenmeier G, Hemdan NY, Kurz S, Bigl M, Pieroh P, Debebe T, Buchold M, Thieme R, Wichmann G, Dehghani F (2016). Ethyl Pyruvate Combats Human Leukemia Cells but Spares Normal Blood Cells. PLoS One, 11(8), e0161571.
     
  213. Debebe T, Holtze S, Morhart M, Hildebrandt TB, Rodewald S, Huse K, Platzer M, Wyohannes D, Yirga S, Lemma A, Thieme R, Konig B, Birkenmeier G (2016). Analysis of cultivable microbiota and diet intake pattern of the long-lived naked mole-rat. Gut Pathog, 8, 25.
     
  214. Langenhan T, Piao X, Monk KR (2016). Adhesion G protein-coupled receptors in nervous system development and disease. Nat Rev Neurosci, 17(9), 550-561.
     
  215. Debebe T, Kruger M, Huse K, Kacza J, Muhlberg K, Konig B, Birkenmeier G (2016). Ethyl Pyruvate: An Anti-Microbial Agent that Selectively Targets Pathobionts and Biofilms. PLoS One, 11(9), e0162919-9.
     
  216. Lede V, Franke C, Meusel A, Teupser D, Ricken A, Thiery J, Schiller J, Huster D, Schoneberg T, Schulz A (2016). Severe Atherosclerosis and Hypercholesterolemia in Mice Lacking Both the Melanocortin Type 4 Receptor and Low Density Lipoprotein Receptor. PLoS One, 11(12), e0167888.
     
  217. Hutschenreuther A, Bigl M, Hemdan NY, Debebe T, Gaunitz F, Birkenmeier G (2016). Modulation of GLO1 Expression Affects Malignant Properties of Cells. Int J Mol Sci, 17(12), E2133.
     
  218. Orthgiess J, Gericke M, Immig K, Schulz A, Hirrlinger J, Bechmann I, Eilers J (2016). Neurons exhibit Lyz2 promoter activity in vivo: Implications for using LysM-Cre mice in myeloid cell research. Eur J Immunol, 46(6), 1529-1532.
     
  219. Marcos R, Lopes C, Malhao F, Correia-Gomes C, Fonseca S, Lima M, Gebhardt R, Rocha E (2016). Stereological assessment of sexual dimorphism in the rat liver reveals differences in hepatocytes and Kupffer cells but not hepatic stellate cells. J Anat, 228(6), 996-1005.
     
  220. Ghallab A, Celliere G, Henkel SG, Driesch D, Hoehme S, Hofmann U, Zellmer S, Godoy P, Sachinidis A, Blaszkewicz M, Reif R, Marchan R, Kuepfer L, Haussinger D, Drasdo D, Gebhardt R, Hengstler JG (2016). Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases. J Hepatol, 64(4), 860-871.
     
  221. Merkwitz C, Blaschuk O, Eplinius F, Winkler J, Promel S, Schulz A, Ricken A (2016). A simple method for inducing estrous cycle stage-specific morphological changes in the vaginal epithelium of immature female mice. Lab Anim, 50(5), 344-353.
     
  222. Merkwitz C, Blaschuk O, Schulz A, Ricken AM (2016). Comments on Methods to Suppress Endogenous?Galactosidase Activity in Mouse Tissues Expressing the LacZ Reporter Gene. J Histochem Cytochem, 64(10), 579-586.
     
  223. Backhaus P, Langenhan T, Neuser K (2016). Effects of transgenic expression of botulinum toxins in Drosophila. J Neurogenet, 30(1), 22-31.
     
  224. Godoy P, Widera A, Schmidt-Heck W, Campos G, Meyer C, Cadenas C, Reif R, Stober R, Hammad S, Putter L, Gianmoena K, Marchan R, Ghallab A, Edlund K, Nussler A, Thasler WE, Damm G, Seehofer D, Weiss TS, (2016). Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue. Arch Toxicol, 90(10), 2513-2529.
     
  225. Voiculescu SE, Le Duc D, Rosca AE, Zeca V, Chitimus DM, Arsene AL, Dragoi CM, Nicolae AC, Zagrean L, Schoneberg T, Zagrean AM (2016). Behavioral and molecular effects of prenatal continuous light exposure in the adult rat. Brain Res, 1650, 51-59.
     
  226. Langenhan T, Schöneberg T (2016). Adhesion G Protein-coupled Receptors. In: Langenhan T, Schöneberg T, Molecular, Physiological and Pharmacological Principles in Health and Disease. (S. 1-403), Switzerland: Springer Verlag.
     
  227. Strutt D, Schnabel R, Fiedler F, Promel S (2016). Adhesion GPCRs Govern Polarity of Epithelia and Cell Migration. In: Langenhahn T, Schoneberg T, Handbook of Experimental Pharmacology. (S. 249-274), Berlin: Springer Verlag.
     
  228. Kovacs P, Schoneberg T (2016). The Relevance of Genomic Signatures at Adhesion GPCR Loci in Humans. In: Langenhahn T, Schoneberg T, Handbook of Experimental Pharmacology. (S. 179-217), Berlin: Springer Verlag.
     
  229. Liebscher I, Schoneberg T (2016). Tethered Agonism: A Common Activation Mechanism of Adhesion GPCRs. In: Langenhahn T, Schoneberg T, Handbook of experimental pharmacology. (S. 111-125), Berlin: Springer Verlag.
     
  230. Nieberler M, Kittel RJ, Petrenko AG, Lin HH, Langenhan T (2016). Control of Adhesion GPCR Function Through Proteolytic Processing. In: Langenhahn T, Schoneberg T, Handbook of experimental pharmacology. (S. 83-109), Berlin: Springer Verlag.
     
  231. Scholz N, Monk KR, Kittel RJ, Langenhan T (2016). Adhesion GPCRs as a Putative Class of Metabotropic Mechanosensors. In: Langenhahn T, Schoneberg T, Handbook of experimental pharmacology. (S. 221-247), Berlin: Springer Verlag.
     


    232. 2015


  232. Preissler J, Grosche A, Lede V, Le Duc D, Krugel K, Matyash V, Szulzewsky F, Kallendrusch S, Immig K, Kettenmann H, Bechmann I, Schoneberg T, Schulz A (2015). Altered microglial phagocytosis in GPR34-deficient mice. Glia, 63(2), 206-215.
     
  233. Petersen SC, Luo R, Liebscher I, Giera S, Jeong SJ, Mogha A, Ghidinelli M, Feltri ML, Schoneberg T, Piao X, Monk KR (2015). The Adhesion GPCR GPR126 Has Distinct, Domain-Dependent Functions in Schwann Cell Development Mediated by Interaction with Laminin-211. Neuron, 85(4), 755-769.
     
  234. Ueberham E, Glockner P, Gohler C, Straub BK, Teupser D, Schonig K, Braeuning A, Hohn AK, Jerchow B, Birchmeier W, Gaunitz F, Arendt T, Sansom O, Gebhardt R, Ueberham U (2015). Global increase of p16INK4a in APC-deficient mouse liver drives clonal growth of p16INK4a-negative tumors. Mol Cancer Res, 13(2), 239-249.
     
  235. Thiel C, Schneckener S, Krauss M, Ghallab A, Hofmann U, Kanacher T, Zellmer S, Gebhardt R, Hengstler JG, Kuepfer L (2015). A systematic evaluation of the use of physiologically based pharmacokinetic modeling for cross-species extrapolation. J Pharm Sci, 104(1), 191-206.
     
  236. Staubert C, Bhuiyan H, Lindahl A, Broom OJ, Zhu Y, Islam S, Linnarsson S, Lehtio J, Nordstrom A (2015). Rewired metabolism in drug-resistant leukemia cells: a metabolic switch hallmarked by reduced dependence on exogenous glutamine. J Biol Chem, 290, 8348-8359.
     
  237. Le Duc D, Spataru A, Ceanga M, Zagrean L, Schoneberg T, Toescu EC, Zagrean AM (2015). Developmental exposure to ethanol increases the neuronal vulnerability to oxygen-glucose deprivation in cerebellar granule cell cultures. Brain Res, 1614, 1-13.
     
  238. Stingu CS, Borgmann T, Rodloff AC, Vielkind P, Jentsch H, Schellenberger W, Eschrich K (2015). Rapid identification of oral Actinomyces species cultivated from subgingival biofilm by MALDI-TOF-MS. J Oral Microbiol, 7, 26110.
     
  239. Thieme R, Kurz S, Kolb M, Debebe T, Holtze S, Morhart M, Huse K, Szafranski K, Platzer M, Hildebrandt TB, Birkenmeier G (2015). Analysis of Alpha-2 Macroglobulin from the Long-Lived and Cancer-Resistant Naked Mole-Rat and Human Plasma. PLoS One, 10(6), e0130470.
     
  240. Le Duc D, Renaud G, Krishnan A, Almen MS, Huynen L, Prohaska SJ, Ongyerth M, Bitarello BD, Schioth HB, Hofreiter M, Stadler PF, Prufer K, Lambert D, Kelso J, Schoneberg T (2015). Kiwi genome provides insights into evolution of a nocturnal lifestyle. Genome Biol, 16(1), 147.
     
  241. Schmidt-Heck W, Matz-Soja M, Aleithe S, Marbach E, Guthke R, Gebhardt R (2015). Fuzzy modeling reveals a dynamic self-sustaining network of the GLI transcription factors controlling important metabolic regulators in adult mouse hepatocytes. Mol Biosyst, 11(8), 2190-2197.
     
  242. Demberg LM, Rothemund S, Schoneberg T, Liebscher I (2015). Identification of the tethered peptide agonist of the adhesion G protein-coupled receptor GPR64/ADGRG2. Biochem Biophys Res Commun, 464(3), 743-747.
     
  243. Monk KR, Hamann J, Langenhan T, Nijmeijer S, Schoneberg T, Liebscher I (2015). Adhesion G Protein-Coupled Receptors: From In Vitro Pharmacology to In Vivo Mechanisms. Mol Pharmacol, 88(3), 617-623.
     
  244. Bottger J, Arnold K, Thiel C, Rennert C, Aleithe S, Hofmann U, Vlaic S, Sales S, Shevchenko A, Matz-Soja M (2015). RNAi in murine hepatocytes: the agony of choice-a study of the influence of lipid-based transfection reagents on hepatocyte metabolism. Arch Toxicol, 89(9), 1579-1588.
     
  245. Gebhardt R, Matz-Soja M (2015). Liposomes as carriers: not as innocent as one would like. Editorial. Arch Toxicol, 89(9), 1399-1400.
     
  246. Worku N, Stich A, Daugschies A, Wenzel I, Kurz R, Thieme R, Kurz S, Birkenmeier G (2015). Ethyl Pyruvate Emerges as a Safe and Fast Acting Agent against Trypanosoma brucei by Targeting Pyruvate Kinase Activity. PLoS One, 10(9), e0137353.
     
  247. Schoneberg T, Liebscher I, Luo R, Monk KR, Piao X (2015). Tethered agonists: a new mechanism underlying adhesion G protein-coupled receptor activation. J Recept Signal Transduct Res, 35(3), 220-223.
     
  248. Staubert C, Broom OJ, Nordstrom A (2015). Hydroxycarboxylic acid receptors are essential for breast cancer cells to control their lipid/fatty acid metabolism. Oncotarget, 6(23), 19706-19720.
     
  249. Liebscher I, Monk KR, Schoneberg T (2015). How to wake a giant. Editorial. Oncotarget, 6(27), 23038-23039.
     
  250. Muller A, Winkler J, Fiedler F, Sastradihardja T, Binder C, Schnabel R, Kungel J, Rothemund S, Hennig C, Schoneberg T, Promel S (2015). Oriented Cell Division in the C. elegans Embryo Is Coordinated by G-Protein Signaling Dependent on the Adhesion GPCR LAT-1. PLoS Genet, 11(10), e1005624.
     
  251. Coster M, Biebermann H, Schoneberg T, Staubert C (2015). Evolutionary Conservation of 3-Iodothyronamine as an Agonist at the Trace Amine-Associated Receptor 1. Eur Thyroid J, 4(Suppl1), 9-20.
     
  252. Le Duc D (2015). Fetal alcohol spectrum disorder: molecular insights into neural damage reduction. Neural Regen Res, 10, 1764-1766.
     
  253. Hamann J, Aust G, Arac D, Engel FB, Formstone C, Fredriksson R, Hall RA, Harty BL, Kirchhoff C, Knapp B, Krishnan A, Liebscher I, Lin HH, Martinelli DC, Monk KR, Peeters MC, Piao X, Promel S, et al. (2015). International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein-Coupled Receptors. Pharmacol Rev, 67(2), 338-367.
     
  254. Dinter J, Muhlhaus J, Wienchol CL, Yi CX, Nurnberg D, Morin S, Gruters A, Kohrle J, Schoneberg T, Tschop M, Krude H, Kleinau G, Biebermann H (2015). Inverse Agonistic Action of 3-Iodothyronamine at the Human Trace Amine-Associated Receptor 5. PLoS One, 10(2), e0117774.
     
  255. Liu X, Weidle K, Schrock K, Tonjes A, Schleinitz D, Breitfeld J, Stumvoll M, Bottcher Y, Schoneberg T, Kovacs P (2015). Signatures of Natural Selection at the FTO (Fat Mass and Obesity Associated) Locus in Human Populations. PLoS One, 10(2), e0117093.
     
  256. Lorbek G, Perse M, Jeruc J, Juvan P, Gutierrez-Mariscal FM, Lewinska M, Gebhardt R, Keber R, Horvat S, Bjorkhem I, Rozman D (2015). Lessons from hepatocyte-specific Cyp51 knockout mice: impaired cholesterol synthesis leads to oval cell-driven liver injury. Sci Rep, 5, 8777.
     
  257. Schleicher J, Tokarski C, Marbach E, Matz-Soja M, Zellmer S, Gebhardt R, Schuster S (2015). Zonation of hepatic fatty acid metabolism - The diversity of its regulation and the benefit of modeling. Biochim Biophys Acta, 1851(5), 641-656.
     
  258. Schuster S, Penke M, Gorski T, Gebhardt R, Weiss TS, Kiess W, Garten A (2015). FK866-induced NAMPT inhibition activates AMPK and downregulates mTOR signaling in hepatocarcinoma cells. Biochem Biophys Res Commun, 458(2), 334-340.
     
  259. Dinter J, Muhlhaus J, Jacobi SF, Wienchol CL, Coster M, Meister J, Hoefig CS, Muller A, Kohrle J, Gruters A, Krude H, Mittag J, Schoneberg T, Kleinau G, Biebermann H (2015). 3-iodothyronamine differentially modulates alpha-2A-adrenergic receptor-mediated signaling. J Mol Endocrinol, 54(3), 205-216.
     
  260. Kloos M, Bruser A, Kirchberger J, Schoneberg T, Strater N (2015). Crystal structure of human platelet phosphofructokinase-1 locked in an activated conformation. Biochem J, 469(3), 421-432.
     
  261. Muche A, Bigl M, Arendt T, Schliebs R (2015). Expression of vascular endothelial growth factor (VEGF) mRNA, VEGF receptor 2 (Flk-1) mRNA, and of VEGF co-receptor neuropilin (Nrp)-1 mRNA in brain tissue of aging Tg2576 mice by in situ hybridization. Int J Dev Neurosci, 43, 25-34.
     
  262. Vielkind P, Jentsch H, Eschrich K, Rodloff AC, Stingu CS (2015). Prevalence of Actinomyces spp. in patients with chronic periodontitis. Int J Med Microbiol, 305(7), 682-688.
     
  263. Dinter J, Khajavi N, Muhlhaus J, Wienchol CL, Coster M, Hermsdorf T, Staubert C, Kohrle J, Schoneberg T, Kleinau G, Mergler S, Biebermann H (2015). The Multitarget Ligand 3-Iodothyronamine Modulates ß-Adrenergic Receptor 2 Signaling. Eur Thyroid J, 4(Suppl1), 21-29.
     
  264. Bartl M, Pfaff M, Ghallab A, Driesch D, Henkel SG, Hengstler JG, Schuster S, Kaleta C, Gebhardt R, Zellmer S, Li P (2015). Optimality in the zonation of ammonia detoxification in rodent liver. Arch Toxicol, 89(11), 2069-2078.
     


    265. 2014


  265. Busse K, Strotmann R, Strecker K, Wegner F, Devanathan V, Gohla A, Schoneberg T, Schwarz J (2014). Adaptive gene regulation in the Striatum of RGS9-deficient mice. PLoS One, 9(3), e92605.
     
  266. Gebhardt R (2014). Speeding up hepatocyte proliferation: How triiodothyronine and ß-catenin join forces. Editorial. Hepatology, 59(6), 2074-2076.
     
  267. Matz-Soja M, Aleithe S, Marbach E, Bottger J, Arnold K, Schmidt-Heck W, Kratzsch J, Gebhardt R (2014). Hepatic Hedgehog signaling contributes to the regulation of IGF1 and IGFBP1 serum levels. Cell Commun Signal, 12, 11.
     
  268. Gebhardt R, Matz-Soja M (2014). Liver zonation: Novel aspects of its regulation and its impact on homeostasis. World J Gastroenterol, 20(26), 8491-8504.
     
  269. Meister J, Le Duc D, Ricken A, Burkhardt R, Thiery J, Pfannkuche H, Polte T, Grosse J, Schoneberg T, Schulz A (2014). The G Protein-coupled Receptor P2Y14 Influences Insulin Release and Smooth Muscle Function in Mice. J Biol Chem, 289(34), 23353-23366.
     
  270. Baunacke M, Horn LC, Trettner S, Engel KM, Hemdan NY, Wiechmann V, Stolzenburg JU, Bigl M, Birkenmeier G (2014). Exploring glyoxalase 1 expression in prostate cancer tissues: targeting the enzyme by ethyl pyruvate defangs some malignancy-associated properties. Prostate, 74(1), 48-60.
     
  271. Trettner S, Findeisen A, Taube S, Horn PA, Sasaki E, zur Nieden NI (2014). Osteogenic induction from marmoset embryonic stem cells cultured in feeder-dependent and feeder-independent conditions. Osteoporos Int, 25(4), 1255-1266.
     
  272. Heyne HO, Lautenschlager S, Nelson R, Besnier F, Rotival M, Cagan A, Kozhemyakina R, Plyusnina IZ, Trut L, Carlborg O, Petretto E, Kruglyak L, Paabo S, Schoneberg T, Albert FW (2014). Genetic influences on brain gene expression in rats selected for tameness and aggression. Genetics, 198(3), 1277-1290.
     
  273. Matz-Soja M, Gebhardt R (2014). The many faces of Hedgehog signalling in the liver: Recent progress reveals striking cellular diversity and the importance of microenvironments. J Hepatol, 61(6), 1449-1450.
     
  274. Liebscher I, Schon J, Petersen SC, Fischer L, Auerbach N, Demberg LM, Mogha A, Coster M, Simon KU, Rothemund S, Monk KR, Schoneberg T (2014). A Tethered Agonist within the Ectodomain Activates the Adhesion G Protein-Coupled Receptors GPR126 and GPR133. Cell Rep, 9(6), 2018-2026.
     
  275. Liebscher I, Ackley B, Arac D, Ariestanti DM, Aust G, Bae BI, Bista BR, Bridges JP, Duman JG, Engel FB, Giera S, Goffinet AM, Hall RA, Hamann J, Hartmann N, Lin HH, Liu M, Luo R, Mogha A, Monk KR, Peeters MC, Promel S, Ressl S, Schioth HB, Sigoillot SM, Song H, Talbot WS, Tall GG, White JP, Wolfrum U, Xu L, Piao X (2014). New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors. Ann N Y Acad Sci, 1333(1), 43-64.
     
  276. Kloos M, Bruser A, Kirchberger J, Schoneberg T, Strater N (2014). Crystallization and preliminary crystallographic analysis of human muscle phosphofructokinase, the main regulator of glycolysis. Acta Crystallogr F Struct Biol Commun, 70(Pt5), 578-582.
     
  277. Hammad S, Hoehme S, Friebel A, von Recklinghausen I, Othman A, Begher-Tibbe B, Reif R, Godoy P, Johann T, Vartak A, Golka K, Bucur PO, Vibert E, Marchan R, Christ B, Dooley S, Meyer C, Ilkavets I, Dah (2014). Protocols for staining of bile canalicular and sinusoidal networks of human, mouse and pig livers, three-dimensional reconstruction and quantification of tissue microarchitecture by image processing and analysis. Arch Toxicol, 88(5), 1161-1183.
     
  278. Schuster S, Penke M, Gorski T, Petzold-Quinque S, Damm G, Gebhardt R, Kiess W, Garten A (2014). Resveratrol differentially regulates NAMPT and SIRT1 in Hepatocarcinoma cells and primary human hepatocytes. PLoS One, 9(3), e91045.
     
  279. Borte S, Meeths M, Liebscher I, Krist K, Nordenskjold M, Hammarstrom L, von Dobeln U, Henter JI, Bryceson YT (2014). Combined newborn screening for familial hemophagocytic lymphohistiocytosis and severe T- and B-cell immunodeficiencies. J Allergy Clin Immunol, 134(1), 226-228.
     
  280. Mates N, Kettner K, Heidenreich F, Pursche T, Migotti R, Kahlert G, Kuhlisch E, Breunig KD, Schellenberger W, Dittmar G, Hoflack B, Kriegel TM (2014). Proteomic and functional consequences of hexokinase deficiency in glucose-repressible Kluyveromyces lactis. Mol Cell Proteomics, 13(3), 860-875.
     
  281. Jentsch HF, Eckert FR, Eschrich K, Stratul SI, Kneist S (2014). Antibacterial action of Chlorhexidine/thymol containing varnishes in vitro and in vivo. Int J Dent Hyg, 12(3), 168-173.
     
  282. Pieroh P, Birkenmeier G, Dehghani F (2014). The temporal and spatial dynamics of glyoxalase I following excitoxicity and brain ischaemia. Biochem Soc Trans, 42(2), 534-537.
     
  283. Pieroh P, Koch M, Wagner DC, Boltze J, Ehrlich A, Ghadban C, Hobusch C, Birkenmeier G, Dehghani F (2014). Temporal dynamics of glyoxalase 1 in secondary neuronal injury. PLoS One, 9(2), e87364.
     
  284. Pyttel S, Nimptsch A, Bottger J, Zschornig K, Jakop U, Wegener J, Muller K, Paasch U, Schiller J (2014). Changes of murine sperm phospholipid composition during epididymal maturation determined by MALDI-TOF mass spectrometry. Theriogenology, 82(2), 396-402.
     
  285. Kern M, Kosacka J, Hesselbarth N, Bruckner J, Heiker JT, Flehmig G, Kloting I, Kovacs P, Matz-Soja M, Gebhardt R, Krohn K, Sales S, Abshagen K, Shevchenko A, Stumvoll M, Bluher M, Kloting N (2014). Liver-restricted repin1 deficiency improves whole-body insulin sensitivity, alters lipid metabolism, and causes secondary changes in adipose tissue in mice. Diabetes, 63(10), 3295-3309.
     
  286. Drasdo D, Bode J, Dahmen U, Dirsch O, Dooley S, Gebhardt R, Ghallab A, Godoy P, Haussinger D, Hammad S, Hoehme S, Holzhutter HG, Klingmuller U, Kuepfer L, Timmer J, Zerial M, Hengstler JG (2014). The virtual liver: state of the art and future perspectives. Arch Toxicol, 88(12), 2071-2075.
     
  287. Schliess F, Hoehme S, Henkel SG, Ghallab A, Driesch D, Bottger J, Guthke R, Pfaff M, Hengstler JG, Gebhardt R, Haussinger D, Drasdo D, Zellmer S (2014). Integrated metabolic spatial-temporal model for the prediction of ammonia detoxification during liver damage and regeneration. Hepatology, 60(6), 2040-2051.
     
  288. Stäubert C, Le Duc D, Schöneberg T (2014). Examining the Dynamic Evolution of G Protein-Coupled Receptors. In: Stevens CW, G Protein-Coupled Receptor Genetics: Research and Methods in the Post-Genomic Era. (S. 23-44), New York: Springer Verlag.
     


    289. 2013


  289. Staubert C, Bohnekamp J, Schoneberg T (2013). Determinants involved in subtype-specific functions of rat trace amine-associated receptors 1 and 4. Br J Pharmacol, 168(5), 1266-1278.
     
  290. Schmidt P, Ritscher L, Dong EN, Hermsdorf T, Coster M, Wittkopf D, Meiler J, Schoneberg T (2013). Identification of Determinants Required for Agonistic and Inverse Agonistic Ligand Properties at the ADP Receptor P2Y12. Mol Pharmacol, 83(1), 256-266.
     
  291. Matz-Soja M, Hovhannisyan A, Gebhardt R (2013). Hedgehog signalling pathway in adult liver: a major new player in hepatocyte metabolism and zonation? Med Hypotheses, 80(5), 589-594.
     
  292. Gebhardt R, Coffer PJ (2013). Hepatic autophagy is differentially regulated in periportal and pericentral zones - a general mechanism relevant for other tissues? Cell Commun Signal, 11(1), 21.
     
  293. Heise K, Oppermann H, Meixensberger J, Gebhardt R, Gaunitz F (2013). Dual Luciferase Assay for Secreted Luciferases Based on Gaussia and NanoLuc. Assay Drug Dev Technol, 11(4), 244-252.
     
  294. Schoneberg T, Kloos M, Bruser A, Kirchberger J, Strater N (2013). Structure and allosteric regulation of eukaryotic 6-phosphofructokinases. Biol Chem, 394(8), 977-993.
     
  295. Liebscher I, Schoneberg T, Promel S (2013). Progress in demystification of adhesion G protein-coupled receptors. Biol Chem, 394(8), 937-950.
     
  296. Promel S, Langenhan T, Arac D (2013). Matching structure with function: the GAIN domain of Adhesion-GPCR and PKD1-like proteins. Trends Pharmacol Sci, 34(8), 470-478.
     
  297. Schaumann R, Knoop N, Genzel GH, Losensky K, Rosenkranz C, Stingu CS, Schellenberger W, Rodloff AC, Eschrich K (2013). Discrimination of Enterobacteriaceae and Non-fermenting Gram Negative Bacilli by MALDI-TOF Mass Spectrometry. Open Microbiol J, 7, 118-122.
     
  298. Maurer K, Eschrich K, Schellenberger W, Bertolini J, Rupf S, Remmerbach TW (2013). Oral brush biopsy analysis by MALDI-ToF Mass Spectrometry for early cancer diagnosis. Oral Oncol, 49(2), 152-156.
     
  299. Prömel S, Aust G, Langenhan T, Schöneberg T (2013). Adhäsions-G-Protein-gekoppelte Rezeptoren – rätselhafte Riesen BIOspektrum, 7, 717-719.
     
  300. Hutschenreuther A, Birkenmeier G, Bigl M, Krohn K, Birkemeyer C (2013). Glycerophosphoglycerol, Beta-Alanine, and Pantothenic Acid as Metabolic Companions of Glycolytic Activity and Cell Migration in Breast Cancer Cell Lines. Metabolites, 3, 1084-1101.
     
  301. Mogha A, Benesh AE, Patra C, Engel FB, Schoneberg T, Liebscher I, Monk KR (2013). Gpr126 Functions in Schwann Cells to Control Differentiation and Myelination via G-Protein Activation. J Neurosci, 33(46), 17976-17985.
     
  302. Stingu CS, Schaumann R, Jentsch H, Eschrich K, Brosteanu O, Rodloff AC (2013). Association of periodontitis with increased colonization by Prevotella nigrescens. J Investig Clin Dent, 4(1), 20-5.
     
  303. Siekmeyer M, Petzold-Quinque S, Terpe F, Beblo S, Gebhardt R, Schlensog-Schuster F, Kiess W, Siekmeyer W (2013). Citric acid as the last therapeutic approach in an acute life-threatening metabolic decompensation of propionic acidaemia. J Pediatr Endocrinol Metab, 26(5-6), 569-574.
     
  304. Merkwitz C, Lochhead P, Bottger J, Matz-Soja M, Sakurai M, Gebhardt R, Ricken AM (2013). Dual origin, development, and fate of bovine pancreatic islets. J Anat, 222(3), 358-371.
     
  305. Prado-Martinez J, Hernando-Herraez I, Lorente-Galdos B, Dabad M, Ramirez O, Baeza-Delgado C, Morcillo-Suarez C, Alkan C, Hormozdiari F, Rainieri E, Estelle J, Fernandez-Callejo M, Valles M, Ritscher L (2013). The genome sequencing of an albino Western lowland gorilla reveals inbreeding in the wild. BMC Genomics, 14, 363.
     
  306. Guernsey MW, Ritscher L, Miller MA, Smith DA, Schoneberg T, Shapiro MD (2013). A Val85Met Mutation in Melanocortin-1 Receptor Is Associated with Reductions in Eumelanic Pigmentation and Cell Surface Expression in Domestic Rock Pigeons (Columba livia). PLoS One, 8(8), e74475.
     
  307. Godoy P, Hewitt NJ, Albrecht U, Andersen ME, Ansari N, Bhattacharya S, Bode JG, Bolleyn J, Borner C, Bottger J, Braeuning A, Budinsky RA, Burkhardt B, Cameron NR, Camussi G, Cho CS, Choi YJ, Craig Row (2013). Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. Arch Toxicol, 87(8), 1315-1530.
     
  308. Merkwitz C, Blaschuk OW, Schulz A, Lochhead P, Meister J, Ehrlich A, Ricken AM (2013). The ductal origin of structural and functional heterogeneity between pancreatic islets. Prog Histochem Cytochem, 48(3), 103-140.
     


    309. 2012


  309. Promel S, Frickenhaus M, Hughes S, Mestek L, Staunton D, Woollard A, Vakonakis I, Schoneberg T, Schnabel R, Russ AP, Langenhan T (2012). The GPS Motif Is a Molecular Switch for Bimodal Activities of Adhesion Class G Protein-Coupled Receptors. Cell Rep, 2(2), 321-331.
     
  310. Boselt I, Tramma D, Kalamitsou S, Niemeyer T, Nykanen P, Graf KJ, Krude H, Marenzi KS, Di Candia S, Schoneberg T, Schulz A (2012). Functional characterization of novel loss-of-function mutations in the vasopressin type 2 receptor gene causing nephrogenic diabetes insipidus. Nephrol Dial Transplant, 27(4), 1521-1528.
     
  311. Ritscher L, Engemaier E, Staubert C, Liebscher I, Schmidt P, Hermsdorf T, Rompler H, Schulz A, Schoneberg T (2012). The ligand specificity of the G-protein-coupled receptor GPR34. Biochem J, 443, 841-850.
     
  312. Bruser A, Kirchberger J, Kloos M, Strater N, Schoneberg T (2012). Functional linkage of adenine nucleotide binding sites in Mammalian muscle 6-phosphofructokinase. J Biol Chem, 287(21), 17546-17553.
     
  313. Coster M, Wittkopf D, Kreuchwig A, Kleinau G, Thor D, Krause G, Schoneberg T (2012). Using ortholog sequence data to predict the functional relevance of mutations in G-protein-coupled receptors. FASEB J, 26(8), 3273-3281.
     
  314. Promel S, Waller-Evans H, Dixon J, Zahn D, Colledge WH, Doran J, Carlton MB, Grosse J, Schoneberg T, Russ AP, Langenhan T (2012). Characterization and functional study of a cluster of four highly conserved orphan adhesion-GPCR in mouse. Dev Dyn, 241(10), 1591-1602.
     
  315. Bruser A, Kirchberger J, Schoneberg T (2012). Altered allosteric regulation of muscle 6-phosphofructokinase causes Tarui disease. Biochem Biophys Res Commun, 427(1), 133-137.
     
  316. Melchior C, Schulz A, Windholz J, Kiess W, Schoneberg T, Korner A (2012). Clinical and Functional Relevance of Melanocortin-4 Receptor Variants in Obese German Children. Horm Res Paediatr, 78(4), 237-246.
     
  317. Schaumann R, Knoop N, Genzel GH, Losensky K, Rosenkranz C, Stingu CS, Schellenberger W, Rodloff AC, Eschrich K (2012). A step towards the discrimination of beta-lactamase-producing clinical isolates of Enterobacteriaceae and Pseudomonas aeruginosa by MALDI-TOF mass spectrometry. Med Sci Monit, 18(9), 71-77.
     
  318. Vlaic S, Schmidt-Heck W, Matz-Soja M, Marbach E, Linde J, Meyer-Baese A, Zellmer S, Guthke R, Gebhardt R (2012). The Extended TILAR Approach: A novel tool for dynamic modeling of the transcription factor network regulating the adaption to in vitro cultivation of murine hepatocytes. BMC Syst Biol, 6, 147.
     
  319. Vasilj A, Gentzel M, Ueberham E, Gebhardt R, Shevchenko A (2012). Tissue proteomics by one-dimensional gel electrophoresis combined with label-free protein quantification. J Proteome Res, 11(7), 3680-3689.
     
  320. Schaab M, Kausch H, Klammt J, Nowicki M, Anderegg U, Gebhardt R, Rose-John S, Scheller J, Thiery J, Kratzsch J (2012). Novel regulatory mechanisms for generation of the soluble leptin receptor: implications for leptin action. PLoS One, 7(4), e34787.
     
  321. Niklas J, Bonin A, Mangin S, Bucher J, Kopacz S, Matz-Soja M, Thiel C, Gebhardt R, Hofmann U, Mauch K (2012). Central energy metabolism remains robust in acute steatotic hepatocytes challenged by a high free fatty acid load. BMB Rep, 45(7), 396-401.
     
  322. van der Vos KE, Eliasson P, Proikas-Cezanne T, Vervoort SJ, van Boxtel R, Putker M, van Zutphen IJ, Mauthe M, Zellmer S, Pals C, Verhagen LP, Groot Koerkamp MJ, Braat AK, Dansen TB, Holstege FC, Gebha (2012). Modulation of glutamine metabolism by the PI(3)K-PKB-FOXO network regulates autophagy. Nat Cell Biol, 14(8), 829-837.
     
  323. Braun S, Oppermann H, Mueller A, Renner C, Hovhannisyan A, Baran-Schmidt R, Gebhardt R, Hipkiss A, Thiery J, Meixensberger J, Gaunitz F (2012). Hedgehog signaling in glioblastoma multiforme. Cancer Biol Ther, 13(7), 487-495.
     
  324. Tarnow P, Rediger A, Schulz A, Gruters A, Biebermann H (2012). Identification of the translation start site of the human melanocortin 3 receptor. Obes Facts, 5(1), 45-51.
     
  325. Hemdan NY, Birkenmeier G, Wichmann G (2012). Key molecules in the differentiation and commitment program of T helper 17 (Th17) cells up-to-date. Immunol Lett, 148(2), 97-109.
     
  326. Gregory AP, Dendrou CA, Attfield KE, Haghikia A, Xifara DK, Butter F, Poschmann G, Kaur G, Lambert L, Leach OA, Promel S, Punwani D, Felce JH, Davis SJ, Gold R, Nielsen FC, Siegel RM, Mann M, Bell JI, (2012). TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis. Nature, 488(7412), 508-511.
     
  327. Hu J, Thor D, Zhou Y, Liu T, Wang Y, McMillin SM, Mistry R, Challiss RA, Costanzi S, Wess J (2012). Structural aspects of M3 muscarinic acetylcholine receptor dimer formation and activation. FASEB J, 26(2), 604-616.
     
  328. Rossol M, Pierer M, Raulien N, Quandt D, Meusch U, Rothe K, Schubert K, Schoneberg T, Schaefer M, Krugel U, Smajilovic S, Brauner-Osborne H, Baerwald C, Wagner U (2012). Extracellular Ca(2+) is a danger signal activating the NLRP3 inflammasome through G protein-coupled calcium sensing receptors. Nat Commun, 3, 1329.
     
  329. Arac D, Aust G, Calebiro D, Engel FB, Formstone C, Goffinet A, Hamann J, Kittel RJ, Liebscher I, Lin HH, Monk KR, Petrenko A, Piao X, Promel S, Schioth HB, Schwartz TW, Stacey M, Ushkaryov YA, Wobus M (2012). Dissecting signaling and functions of adhesion G protein-coupled receptors. Ann N Y Acad Sci, 1276(1), 1-25.
     
  330. Birkenmeier G (2012). "Enzyme" In: Münstedt K, "Komplementäre und alternative Krebstherapien" (S. 579-586), Landsberg/Lech: ecomed Medizin.
     


    331. 2011


  331. Liebscher I, Muller U, Teupser D, Engemaier E, Engel KM, Ritscher L, Thor D, Sangkuhl K, Ricken A, Wurm A, Piehler D, Schmutzler S, Fuhrmann H, Albert FW, Reichenbach A, Thiery J, Schoneberg T, Schulz (2011). Altered immune response in mice deficient for the G protein-coupled receptor GPR34. J Biol Chem, 286(3), 2101-2110.
     
  332. Strater N, Marek S, Kuettner EB, Kloos M, Keim A, Bruser A, Kirchberger J, Schoneberg T (2011). Molecular architecture and structural basis of allosteric regulation of eukaryotic phosphofructokinases. FASEB J, 25(1), 89-98.
     
  333. Strotmann R, Schrock K, Boselt I, Staubert C, Russ A, Schoneberg T (2011). Evolution of GPCR: change and continuity. Mol Cell Endocrinol, 331(2), 170-178.
     
  334. Lakner J, Seyer C, Hermsdorf T, Schoneberg T (2011). Characterization of the expression, promoter activity and molecular architecture of fibin. BMC Biochem, 12(1), e26.
     
  335. Bohnekamp J, Schoneberg T (2011). Cell Adhesion Receptor GPR133 Couples to Gs Protein. J Biol Chem, 286(49), 41912-41916.
     
  336. Frenzel J, Gessner C, Sandvoss T, Hammerschmidt S, Schellenberger W, Sack U, Eschrich K, Wirtz H (2011). Outcome prediction in pneumonia induced ALI/ARDS by clinical features and peptide patterns of BALF determined by mass spectrometry. PLoS One, 6(10), e25544.
     
  337. Fleischer M, Kessler R, Klammer A, Warnke JP, Eschrich K (2011). LOH on 10p14-p15 targets the PFKFB3 gene locus in human glioblastomas. Genes Chromosomes Cancer, 50(12), 1010-1020.
     
  338. Engel KM, Schrock K, Teupser D, Holdt LM, Tonjes A, Kern M, Dietrich K, Kovacs P, Krugel U, Scheidt HA, Schiller J, Huster D, Brockmann GA, Augustin M, Thiery J, Bluher M, Stumvoll M, Schoneberg T, Sc (2011). Reduced Food Intake and Body Weight in Mice Deficient for the G Protein-Coupled Receptor GPR82. PLoS One, 6, e29400.
     
  339. Bodensieck A, Gaunitz F, Gebhardt R, Danesch U, Bauer R (2011). Differential and Stereoselective In Vitro Cytotoxicity of Eremophilane Sesquiterpenes of Petasites hybridus Rhizomes in Rat Hepatocytes. Planta Med, 77(1), 32-39.
     
  340. Remmerbach TW, Maurer K, Janke S, Schellenberger W, Eschrich K, Bertolini J, Hofmann H, Rupf S (2011). Oral brush biopsy analysis by matrix assisted laser desorption/ionisation-time of flight mass spectrometry profiling - a pilot study. Oral Oncol, 47(4), 278-281.
     
  341. Banaszak K, Mechin I, Obmolova G, Oldham M, Chang SH, Ruiz T, Radermacher M, Kopperschlager G, Rypniewski W (2011). The crystal structures of eukaryotic phosphofructokinases from baker's yeast and rabbit skeletal muscle. J Mol Biol, 407(2), 284-297.
     
  342. Asperger A, Renner C, Menzel M, Gebhardt R, Meixensberger J, Gaunitz F (2011). Identification of factors involved in the anti-tumor activity of carnosine on glioblastomas using a proteomics approach. Cancer Invest, 29(4), 272-281.
     
  343. Schutte J, Hagmeyer B, Holzner F, Kubon M, Werner S, Freudigmann C, Benz K, Bottger J, Gebhardt R, Becker H, Stelzle M (2011). "Artificial micro organs" - a microfluidic device for dielectrophoretic assembly of liver sinusoids. Biomed Microdevices, 13(3), 493-501.
     
  344. Albert FW, Hodges E, Jensen JD, Besnier F, Xuan Z, Rooks M, Bhattacharjee A, Brizuela L, Good JM, Green RE, Burbano HA, Plyusnina IZ, Trut L, Andersson L, Schoneberg T, Carlborg O, Hannon GJ, Paabo S (2011). Targeted resequencing of a genomic region influencing tameness and aggression reveals multiple signals of positive selection. Heredity, 107(3), 205-214.
     
  345. Rediger A, Piechowski CL, Yi CX, Tarnow P, Strotmann R, Gruters A, Krude H, Schoneberg T, Tschop MH, Kleinau G, Biebermann H (2011). Mutually opposite signal modulation by hypothalamic heterodimerization of ghrelin and melanocortin-3 receptors. J Biol Chem, 286(5), 39623-39631.
     
  346. Kleinau G, Pratzka J, Nurnberg D, Gruters A, Fuhrer-Sakel D, Krude H, Kohrle J, Schoneberg T, Biebermann H (2011). Differential modulation of Beta-adrenergic receptor signaling by trace amine-associated receptor 1 agonists. PLoS One, 6(10), e27073.
     
  347. Bielohuby M, Schaab M, Kummann M, Sawitzky M, Gebhardt R, Binder G, Frystyk J, Bjerre M, Hoeflich A, Kratzsch J, Bidlingmaier M (2011). Serum igf-I is not a reliable pharmacodynamic marker of exogenous growth hormone activity in mice. Endocrinology, 152(12), 4764-4776.
     
  348. Rolyan H, Feike AC, Upadhaya AR, Waha A, Van Dooren T, Haass C, Birkenmeier G, Pietrzik CU, Van Leuven F, Thal DR (2011). Amyloid-β protein modulates the perivascular clearance of neuronal apolipoprotein E in mouse models of Alzheimer's disease. J Neural Transm, 118(5), 699-712.
     
  349. Häussinger D (2011). Animal Models for Studies on Liver Regeneration. In: Häussinger D, Liver Regeneration. (S. 175-190), Berlin/Boston: Walter de Gruyter GmbH & Co. KG.
     


    350. 2010


  350. Hofreiter M, Schoneberg T (2010). The genetic and evolutionary basis of colour variation in vertebrates. Cell Mol Life Sci, 67(15), 2591-2603.
     
  351. Garten A, Petzold S, Barnikol-Oettler A, Korner A, Thasler WE, Kratzsch J, Kiess W, Gebhardt R (2010). Nicotinamide phosphoribosyltransferase (NAMPT/PBEF/visfatin) is constitutively released from human hepatocytes. Biochem Biophys Res Commun, 391(1), 376-381.
     
  352. Pavlica S, Gebhardt R (2010). Protective effects of flavonoids and two metabolites against oxidative stress in neuronal PC12 cells. Life Sci, 86(3-4), 79-86.
     
  353. Pavlica S, Gebhardt R (2010). Comparison of uptake and neuroprotective potential of seven zinc-salts. Neurochem Int, 56(1), 84-93.
     
  354. Gebhardt R, Hovhannisyan A (2010). Organ patterning in the adult stage: the role of Wnt/beta-catenin signaling in liver zonation and beyond. Dev Dyn, 239(1), 45-55.
     
  355. Bohnekamp J, Boselt I, Saalbach A, Tonjes A, Kovacs P, Biebermann H, Manvelyan HM, Polte T, Gasperikova D, Lkhagvasuren S, Baier L, Stumvoll M, Rompler H, Schoneberg T (2010). Involvement of the chemokine-like receptor GPR33 in innate immunity. Biochem Biophys Res Commun, 396(2), 272-277.
     
  356. Strotmann R, Semtner M, Kepura F, Plant TD, Schoneberg T (2010). Interdomain interactions control Ca2+-dependent potentiation in the cation channel TRPV4. PLoS One, 5(5), e 10580.
     
  357. Staubert C, Boselt I, Bohnekamp J, Rompler H, Enard W, Schoneberg T (2010). Structural and Functional Evolution of the Trace Amine-Associated Receptors TAAR3, TAAR4 and TAAR5 in Primates. PLoS One, 5(6), 11133ff.
     
  358. Gebhardt R, Lerche KS, Gotschel F, Gunther R, Kolander J, Teich L, Zellmer S, Hofmann HJ, Eger K, Hecht A, Gaunitz F (2010). 4-Aminoethylamino-emodin - a novel potent inhibitor of GSK-3beta- acts as an insulin-sensitizer avoiding downstream effects of activated beta-catenin. J Cell Mol Med, 14(6a), 1276-1293.
     
  359. Birkenmeier G, Stegemann C, Hoffmann R, Gunther R, Huse K, Birkemeyer C (2010). Posttranslational modification of human glyoxalase 1 indicates redox-dependent regulation. PLoS One, 5(4), 10399.
     
  360. Zellmer S, Schmidt-Heck W, Godoy P, Weng H, Meyer C, Lehmann T, Sparna T, Schormann W, Hammad S, Kreutz C, Timmer J, von Weizsacker F, Thurmann PA, Merfort I, Guthke R, Dooley S, Hengstler JG, Gebhard (2010). Transcription factors ETF, E2F, and SP-1 are involved in cytokine-independent proliferation of murine hepatocytes. Hepatology, 52(6), 2127-2136.
     
  361. Ueberham E, Bottger J, Ueberham U, Grosche J, Gebhardt R (2010). Response of sinusoidal mouse liver cells to choline-deficient ethionine-supplemented diet. Comp Hepatol, 9, 8 ff.
     
  362. Lindner I, Hemdan NY, Buchold M, Huse K, Bigl M, Oerlecke I, Ricken A, Gaunitz F, Sack U, Naumann A, Hollborn M, Thal D, Gebhardt R, Birkenmeier G (2010). Alpha2-macroglobulin inhibits the malignant properties of astrocytoma cells by impeding beta-catenin signaling. Cancer Res, 70(1), 277-287.
     
  363. Halwachs S, Lakoma C, Gebhardt R, Schafer I, Seibel P, Honscha W (2010). Dioxin mediates downregulation of the reduced folate carrier transport activity via the arylhydrocarbon receptor signalling pathway. Toxicol Appl Pharmacol, 246(1-2), 100-106.
     
  364. Hoehme S, Brulport M, Bauer A, Bedawy E, Schormann W, Hermes M, Puppe V, Gebhardt R, Zellmer S, Schwarz M, Bockamp E, Timmel T, Hengstler JG, Drasdo D (2010). Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration. Proc Natl Acad Sci U S A, 107(23), 10371-10376.
     
  365. Renner C, Zemitzsch N, Fuchs B, Geiger KD, Hermes M, Hengstler J, Gebhardt R, Meixensberger J, Gaunitz F (2010). Carnosine retards tumor growth in vivo in an NIH3T3-HER2/neu mouse model. Mol Cancer, 9, 2ff.
     
  366. Turner LM, Young AR, Rompler H, Schoneberg T, Phelps SM, Hoekstra HE (2010). Monogamy evolves through multiple mechanisms: evidence from V1aR in deer mice. Mol Biol Evol, 27(6), 1269-1278.
     
  367. Rosenblum EB, Rompler H, Schoneberg T, Hoekstra HE (2010). Molecular and functional basis of phenotypic convergence in white lizards at White Sands. Proc Natl Acad Sci U S A, 107(5), 2113-2117.
     
  368. Wurm A, Lipp S, Pannicke T, Linnertz R, Krugel U, Schulz A, Farber K, Zahn D, Grosse J, Wiedemann P, Chen J, Schoneberg T, Illes P, Reichenbach A, Bringmann A (2010). Endogenous purinergic signaling is required for osmotic volume regulation of retinal glial cells. J Neurochem, 112(5), 1261-1272.
     
  369. Kretschmer D, Gleske AK, Rautenberg M, Wang R, Koberle M, Bohn E, Schoneberg T, Rabiet MJ, Boulay F, Klebanoff SJ, van Kessel KA, van Strijp JA, Otto M, Peschel A (2010). Human Formyl Peptide Receptor 2 Senses Highly Pathogenic Staphylococcus aureus. Cell Host Microbe, 7(6), 463-473.
     
  370. Renner C, Asperger A, Seyffarth A, Meixensberger J, Gebhardt R, Gaunitz F (2010). Carnosine inhibits ATP production in cells from malignant glioma. Neurol Res, 32(1), 101-105.
     
  371. Ciuclan L, Ehnert S, Ilkavets I, Weng HL, Gaitantzi H, Tsukamoto H, Ueberham E, Meindl-Beinker NM, Singer MV, Breitkopf K, Dooley S (2010). TGF-beta enhances alcohol dependent hepatocyte damage via down-regulation of alcohol dehydrogenase I. J Hepatol, 52(3), 407-416.
     
  372. Kramer M, Backhaus O, Rosenstiel P, Horn D, Klopocki E, Birkenmeier G, Schreiber S, Platzer M, Hampe J, Huse K (2010). Analysis of relative gene dosage and expression differences of the paralogs RABL2A and RABL2B by Pyrosequencing. Gene, 455(1-2), 1-7.
     
  373. Pechkovsky DV, Prasse A, Kollert F, Engel KM, Dentler J, Luttmann W, Friedrich K, Muller-Quernheim J, Zissel G (2010). Alternatively activated alveolar macrophages in pulmonary fibrosis-mediator production and intracellular signal transduction. Clin Immunol, 137(1), 89-101.
     
  374. Schutte J, Freudigmann C, Benz K, Bottger J, Gebhardt R, Stelzle M (2010). A method for patterned in situ biofunctionalization in injection-molded microfluidic devices. Lab Chip, 10(19), 2551-2558.
     
  375. Koesters R, Kaissling B, Lehir M, Picard N, Theilig F, Gebhardt R, Glick AB, Hahnel B, Hosser H, Grone HJ, Kriz W (2010). Tubular overexpression of transforming growth factor-beta1 induces autophagy and fibrosis but not mesenchymal transition of renal epithelial cells. Am J Pathol, 177(2), 632-643.
     
  376. Hemdan NY, Birkenmeier G, Wichmann G, Abu El-Saad AM, Krieger T, Conrad K, Sack U (2010). Interleukin-17-producing T helper cells in autoimmunity. Autoimmun Rev, 9(11), 785-792.
     
  377. Burger S, Yafai Y, Bigl M, Wiedemann P, Schliebs R (2010). Effect of VEGF and its receptor antagonist SU-5416, an inhibitor of angiogenesis, on processing of the β-amyloid precursor protein in primary neuronal cells derived from brain tissue of Tg2576 mice. Int J Dev Neurosci, 28(7), 597-604.
     
  378. Schoneberg T, Schrock K, Staubert C, Russ A (2010). Evolution of the repertoire and structure of G protein-coupled receptors. In: Siehler S, Milligan G, G Protein-coupled Receptors: Structure, Signalling and Physiology. (S. 5-31), Cambridge: Cambridge University Press.
     
  379. Bartl M, Pfaff M, Toepfer S, Zellmer S, Gebhardt R, Schuster S, Li P (2010). Model-based Optimization to explain liver zonation in nitrogen metabolism. In: Scharff P, Crossing Borders within the ABC - Automation, Biomedical Engineering and Computer Science. (S. 235-240), Ilmenau: Verlag ISLE.
     


    380. 2009


  380. Pavlica S, Gaunitz F, Gebhardt R (2009). Comparative in vitro toxicity of seven zinc-salts towards neuronal PC12 cells. Toxicol In Vitro, 23(4), 653-659.
     
  381. Boselt I, Rompler H, Hermsdorf T, Thor D, Busch W, Schulz A, Schoneberg T (2009). Involvement of the v2 vasopressin receptor in adaptation to limited water supply. PLoS One, 4(5), e5573.
     
  382. Melchior C, Kiess W, Dittrich K, Schulz A, Schoneberg T, Korner A (2009). Lean despite a genetic predisposition for obesity--configuration of environmental factors as a chance? A case report Dtsch Med Wochenschr, 134(20), 1047-1050.
     
  383. Thor D, Le Duc D, Strotmann R, Schoneberg T (2009). Luciferase activity under direct ligand-dependent control of a muscarinic acetylcholine receptor. BMC Biotechnol, 9, 46ff.
     
  384. Wierzchacz C, Su E, Kolander J, Gebhardt R (2009). Differential inhibition of matrix metalloproteinases-2, -9, and -13 activities by selected anthraquinones. Planta Med, 75(4), 327-329.
     
  385. Burkhardt JK, Halama D, Frerich B, Gaunitz F (2009). Real-time RT-PCR discriminating mRNA encoding osteocalcin from unspecific targets. Anal Bioanal Chem, 393(4), 1351-1355.
     
  386. Gebhardt R (2009). Prevention of cadmium-induced toxicity in liver-derived cells by the combination preparation Hepeel Environ Toxicol Phar, 27(3), 402-409.
     
  387. Hovhannisyan A, Matz M, Gebhardt R (2009). From Teratogens to Potential Therapeutics: Natural Inhibitors of the Hedgehog Signaling Network Come of Age Planta Med, 75(13), 1371-1380.
     
  388. Zellmer S, Sickinger S, Schmidt-Heck W, Guthke R, Gebhardt R (2009). Heterogeneous expression of suppressor of cytokine signalling 2 (SOCS-2) in liver tissue. J Anat, 215(2), 176-183.
     
  389. Zscharnack K, Kessler R, Bleichert F, Warnke JP, Eschrich K (2009). The PFKFB3 splice variant UBI2K4 is downregulated in high-grade astrocytomas and impedes the growth of U87 glioblastoma cells. Neuropathol Appl Neurobiol, 35(6), 566-578.
     
  390. Kiwanuka GN, Joshi H, Isharaza WK, Eschrich K (2009). Dynamics of Plasmodium falciparum alleles in children with normal haemoglobin and with sickle cell trait in western Uganda. Trans R Soc Trop Med Hyg, 103(1), 87-94.
     
  391. Steiner CC, Rompler H, Boettger LM, Schoneberg T, Hoekstra HE (2009). The genetic basis of phenotypic convergence in beach mice: similar pigment patterns but different genes. Mol Biol Evol, 26(1), 35-45.
     
  392. Sandrock M, Schulz A, Merkwitz C, Schoneberg T, Spanel-Borowski K, Ricken A (2009). Reduction in corpora lutea number in obese melanocortin-4-receptor-deficient mice. Reprod Biol Endocrinol, 7, 24-24.
     
  393. Koch D, Sakurai M, Hummitzsch K, Hermsdorf T, Erdmann S, Schwalbe S, Stolzenburg JU, Spanel-Borowski K, Ricken AM (2009). KIT variants in bovine ovarian cells and corpus luteum. Growth Factors, 27(2), 100-113.
     
  394. Danielyan L, Zellmer S, Sickinger S, Tolstonog GV, Salvetter J, Lourhmati A, Reissig DD, Gleiter CH, Gebhardt R, Buniatian GH (2009). Keratinocytes as depository of ammonium-inducible glutamine synthetase: age- and anatomy-dependent distribution in human and rat skin. PLoS One, 4(2), e4416.
     
  395. Leonhardt K, Gebhardt R, Mossner J, Lutsenko S, Huster D (2009). Functional interactions of Cu-ATPase ATP7B with cisplatin and the role of ATP7B in the resistance of cells to the drug. J Biol Chem, 284(12), 7793-7802.
     
  396. Ueberham U, Lange P, Ueberham E, Bruckner MK, Hartlage-Rubsamen M, Pannicke T, Rohn S, Cross M, Arendt T (2009). Smad2 isoforms are differentially expressed during mouse brain development and aging. Int J Dev Neurosci, 27(5), 501-510.
     
  397. Benjamin S, Radermacher M, Kirchberger J, Schoneberg T, Edelmann A, Ruiz T (2009). 3D structure of phosphofructokinase from Pichia pastoris: Localization of the novel gamma-subunits. J Struct Biol, 168(2), 345-351.
     
  398. Danielyan L, Schafer R, Schulz A, Ladewig T, Lourhmati A, Buadze M, Schmitt AL, Verleysdonk S, Kabisch D, Koeppen K, Siegel G, Proksch B, Kluba T, Eckert A, Kohle C, Schoneberg T, Northoff H, Schwab M (2009). Survival, neuron-like differentiation and functionality of mesenchymal stem cells in neurotoxic environment: the critical role of erythropoietin. Cell Death Differ, 16(12), 1599-1614.
     
  399. Stanchev D, Blosa M, Milius D, Gerevich Z, Rubini P, Schmalzing G, Eschrich K, Schaefer M, Wirkner K, Illes P (2009). Cross-inhibition between native and recombinant TRPV1 and P2X(3) receptors. Pain, 143/1-2), 26-36.
     
  400. Albert FW, Carlborg O, Plyusnina I, Besnier F, Hedwig D, Lautenschläger S, Lorenz D, McIntosh J, Neumann C, Richter H, Zeising C, Kozhemyakina R, Shchepina O, Kratzsch J, Trut L, Teupser D, Thiery J, (2009). Genetic architecture of tameness in a rat model of animal domestication. Genetics, 182(2), 541-554.
     
  401. Wegner F, Kraft R, Busse K, Schaarschmidt G, Hartig W, Schwarz SC, Schwarz J (2009). Glutamate receptor properties of human mesencephalic neural progenitor cells: NMDA enhances dopaminergic neurogenesis in vitro. J Neurochem, 111(1), 204-216.
     
  402. Hofreiter M, Römpler H (2009). Polymerase chain reaction: A blessing and a curse for ancient deoxyribonucleic acid research. In: Bustin SA, The PCR Revolution - Basic Technologies and Applications. (S. 284-300), Cambridge: Cambridge University Press.
     


    403. 2008


  403. Kessler R, Bleichert F, Warnke JP, Eschrich K (2008). 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB3) is up-regulated in high-grade astrocytomas. J Neurooncol, 86(3), 257-264.
     
  404. Austinat M, Dunsch R, Wittekind C, Tannapfel A, Gebhardt R, Gaunitz F (2008). Correlation between beta-catenin mutations and expression of Wnt-signaling target genes in hepatocellular carcinoma. Mol Cancer, 7(1), 21ff.
     
  405. Thor D, Schulz A, Hermsdorf T, Schoneberg T (2008). Generation of an agonistic binding site for blockers of the M(3) muscarinic acetylcholine receptor. Biochem J, 412(1), 103-112.
     
  406. Renner C, Seyffarth A, De Arriba SG, Meixensberger J, Gebhardt R , Gaunitz F (2008). Carnosine inhibits growth of cells isolated from human glioblastoma multiforme. Int J Pept Res Ther, 14(2), 127-135.
     
  407. Stingu CS, Rodloff AC, Jentsch H, Schaumann R, Eschrich K (2008). Rapid identification of oral anaerobic bacteria cultivated from subgingival biofilm by MALDI-TOF-MS. Oral Microbiol Immunol, 23(5), 372-376.
     
  408. Schliebe N, Strotmann R, Busse K, Mitschke D, Biebermann H, Schomburg L, Kohrle J, Bar J, Rompler H, Wess J, Schoneberg T, Sangkuhl K (2008). V2 vasopressin receptor deficiency causes changes in expression and function of renal and hypothalamic components involved in electrolyte and water homeostasis. Am J Physiol Renal Physiol, 295(4), 1177-1190.
     
  409. Bigl M, Jandrig B, Horn LC, Eschrich K (2008). Aberrant methylation of human L- and M-fructose 1,6-bisphosphatase genes in cancer. Biochem Biophys Res Commun, 377(2), 720-724.
     
  410. Santel T, Pflug G, Hemdan NY, Schäfer A, Hollenbach M, Buchold M, Hintersdorf A, Lindner I, Otto A, Bigl M, Oerlecke I, Hutschenreuter A, Sack U, Huse K, Groth M, Birkemeyer C, Schellenberger W, Gebha (2008). Curcumin inhibits glyoxalase 1: a possible link to its anti-inflammatory and anti-tumor activity. PLoS ONE, 3(10), 3508-3508.
     
  411. Hollenbach M, Hintersdorf A, Huse K, Sack U, Bigl M, Groth M, Santel T, Buchold M, Lindner I, Otto A, Sicker D, Schellenberger W, Almendinger J, Pustowoit B, Birkemeyer C, Platzer M, Oerlecke I, Hemda (2008). Ethyl pyruvate and ethyl lactate down-regulate the production of pro-inflammatory cytokines and modulate expression of immune receptors. Biochem Pharmacol, 76(5), 631-644.
     
  412. Ueberham E, Lindner R, Kamprad M, Hiemann R, Hilger N, Woithe B, Mahn D, Cross M, Sack U, Gebhardt R, Arendt T, Ueberham U (2008). Oval cell proliferation in p16INK4a expressing mouse liver is triggered by chronic growth stimuli. J Cell Mol Med, 12(2), 622-638.
     
  413. Birkenmeier G (2008). Oral proteolytic enzymes: mechanism of action and therapeutic aspects Dtsch Med Wochenschr, 133(Suppl 9), S301-302.
     
  414. Gessner C, Dihazi H, Brettschneider S, Hammerschmidt S, Kuhn H, Eschrich K, Keller T, Engelmann L, Sack U, Wirtz H (2008). Presence of cytokeratins in exhaled breath condensate of mechanical ventilated patients. Respir Med, 102(2), 299-306.
     
  415. Hughes DA, Tang K, Strotmann R, Schoneberg T, Prenen J, Nilius B, Stoneking M (2008). Parallel Selection on TRPV6 in Human Populations. PLoS ONE, 3(2), 1686ff.
     
  416. Albert FW, Shchepina O, Winter C, Rompler H, Teupser D, Palme R, Ceglarek U, Kratzsch J, Sohr R, Trut LN, Thiery J, Morgenstern R, Plyusnina IZ, Schoneberg T, Paabo S (2008). Phenotypic differences in behavior, physiology and neurochemistry between rats selected for tameness and for defensive aggression towards humans. Horm Behav, 53(3), 413-421.
     
  417. Sensken SC, Staubert C, Keul P, Levkau B, Schoneberg T, Graler MH (2008). Selective activation of G alpha i mediated signalling of S1P(3) by FTY720-phosphate. Cell Signal, 20(6), 1125-1133.
     
  418. Erdmann S, Ricken A, Hummitzsch K, Merkwitz C, Schliebe N, Gaunitz F, Strotmann R, Spanel-Borowski K (2008). Inflammatory cytokines increase extracellular procathepsin D in permanent and primary endothelial cell cultures. Eur J Cell Biol, 87(5), 311-323.
     
  419. Bryk J, Hardouin E, Pugach I, Hughes D, Strotmann R, Stoneking M, Myles S (2008). Positive selection in East Asians for an EDAR allele that enhances NF-kappaB activation. PLoS ONE, 3(5), 2209ff.
     
  420. Glahn F, Schmidt-Heck W, Zellmer S, Guthke R, Wiese J, Golka K, Hergenroder R, Degen GH, Lehmann T, Hermes M, Schormann W, Brulport M, Bauer A, Bedawy E, Gebhardt R, Hengstler JG, Foth H (2008). Cadmium, cobalt and lead cause stress response, cell cycle deregulation and increased steroid as well as xenobiotic metabolism in primary normal human bronchial epithelial cells which is coordinated by at least nine transcription factors. Arch Toxicol, 82(8), 513-524.
     
  421. Dooley S, Hamzavi J, Ciuclan L, Godoy P, Ilkavets I, Ehnert S, Ueberham E, Gebhardt R, Kanzler S, Geier A, Breitkopf K, Weng H, Mertens PR (2008). Hepatocyte-specific Smad7 expression attenuates TGF-beta-mediated fibrogenesis and protects against liver damage. Gastroenterology, 135(2), 642-659.
     
  422. Schormann W, Hammersen FJ, Brulport M, Hermes M, Bauer A, Rudolph C, Schug M, Lehmann T, Nussler A, Ungefroren H, Hutchinson J, Fandrich F, Petersen J, Wursthorn K, Burda MR, Brustle O, Krishnamurthi (2008). Tracking of human cells in mice. Histochem Cell Biol, 130(2), 329-338.
     
  423. Klinke T, Rump A, Ponisch R, Schellenberger W, Muller EC, Otto A, Klimm W, Kriegel TM (2008). Identification and characterization of CaApe2 - a neutral arginine/alanine/leucine-specific metallo-aminopeptidase from Candida albicans. FEMS Yeast Res, 8(6), 858-869.
     
  424. Lin QS, Weis S, Yang G, Zhuang T, Abate A, Dennery PA (2008). Catalytic inactive heme oxygenase-1 protein regulates its own expression in oxidative stress. Free Radic Biol Med, 44(5), 847-855.
     
  425. Bigl K, Gaunitz F, Schmitt A, Rothemund S, Schliebs R, Munch G, Arendt T (2008). Cytotoxicity of advanced glycation endproducts in human micro- and astroglial cell lines depends on the degree of protein glycation. J Neural Transm, 115(11), 1545-1556.
     
  426. Danielyan LG, Gebhardt R, Buniatian GH (2008). Expression of Glial Fibrillary Acidic Protein in the Rat Endocard, Cardiac Interstitial Cajal-Like Cells, and Perivascular Structures of the Spleen. Neurochemical Journal, 2(4), 293-296.
     
  427. Wegner F, Kraft R, Busse K, Hartig W, Schaarschmidt G, Schwarz SC, Schwarz J, Hevers W (2008). Functional and molecular analysis of GABA receptors in human midbrain-derived neural progenitor cells. J Neurochem, 107(4), 1056-1069.
     
  428. Rupf S, Hannig M, Breitung K, Schellenberger W, Eschrich K, Remmerbach T, Kneist S (2008). Phenotypic Heterogeneity of Streptococcus mutans in Dentin. J Dent Res, 87(12), 1172-1176.
     
  429. Stingu CS, Eschrich K, Rodloff AC, Schaumann R, Jentsch H (2008). Periodontitis is associated with a loss of colonization by Streptococcus sanguinis. J Med Microbiol, 57(Pt 4), 495-499.
     
  430. Joerchel S, Raap M, Bigl M, Eschrich K, Schliebs R (2008). Oligomeric beta-amyloid(1-42) induces the expression of Alzheimer disease-relevant proteins in cholinergic SN56.B5.G4 cells as revealed by proteomic analysis. Int J Dev Neurosci, 26(3-4), 301-308.
     
  431. Gizak A, Maciaszczyk E, Dzugaj A, Eschrich K, Rakus D (2008). Evolutionary conserved N-terminal region of human muscle fructose 1,6-bisphosphatase regulates its activity and the interaction with aldolase. Proteins, 72(1), 209-216.
     
  432. Herrmann P, Druckrey-Fiskaaen C, Kouznetsova E, Heinitz K, Bigl M, Cotman SL, Schliebs R (2008). Developmental impairments of select neurotransmitter systems in brains of Cln3(Deltaex7/8) knock-in mice, an animal model of juvenile neuronal ceroid lipofuscinosis. J Neurosci Res, 86(8), 1857-1870.
     
  433. Utter S, Tamboli IY, Walter J, Upadhaya AR, Birkenmeier G, Pietrzik CU, Ghebremedhin E, Thal DR (2008). Cerebral small vessel disease-induced apolipoprotein E leakage is associated with Alzheimer disease and the accumulation of amyloid beta-protein in perivascular astrocytes. J Neuropathol Exp Neurol, 67(9), 842-856.
     
  434. Huse K, Taudien S, Groth M, Rosenstiel P, Szafranski K, Hiller M, Hampe J, Junker K, Schubert J, Schreiber S, Birkenmeier G, Krawczak M, Platzer M (2008). Genetic variants of the copy number polymorphic beta-defensin locus are associated with sporadic prostate cancer. Tumor Biol, 29(2), 83-92.
     
  435. Groth M, Szafranski K, Taudien S, Huse K, Mueller O, Rosenstiel P, Nygren AO, Schreiber S, Birkenmeier G, Platzer M (2008). High-resolution mapping of the 8p23.1 beta-defensin cluster reveals strictly concordant copy number variation of all genes. Hum Mutat, 29(10), 1247-1254.
     
  436. Knofler G, Purschwitz R, Jentsch H, Birkenmeier G, Schmidt H (2008). Gingival crevicular fluid levels of aspartate aminotransferase and alpha2-macroglobulin before and after topical application of metronidazole or scaling and root planing. Quintessence Int, 39(5), 381-389.
     
  437. Bockamp E, Sprengel R, Eshkind L, Lehmann T, Braun JM, Emmrich F, Hengstler JG (2008). Conditional transgenic mouse models: from the basics to genome-wide sets of knockouts and current studies of tissue regeneration. Regen Med, 3(2), 217-235.
     
  438. Schoneberg T (2008). Tolerance and Desensitization. In: Offermanns S, Rosenthal W, Encyclopedia of Molecular Pharmacology. (S. 1203-1207), Berlin, Heidelberg: Springer Verlag.
     


    439. 2007


  439. Danielyan L, Tolstonog G, Traub P, Salvetter J, Gleiter CH, Reisig D, Gebhardt R, Buniatian GH (2007). Colocalization of Glial Fibrillary Acidic Protein, Metallothionein, and MHC II in Human, Rat, NOD/SCID, and Nude Mouse Skin Keratinocytes and Fibroblasts. J Invest Dermatol, 127(3), 555-563.
     
  440. Plant TD, Strotmann R (2007). TRPV4. Handb Exp Pharmacol, (179), 189-205.
     
  441. Schoneberg T, Hofreiter M, Schulz A, Rompler H (2007). Learning from the past: evolution of GPCR functions. Trends Pharmacol Sci, 28(3), 117-121.
     
  442. Rompler H, Staubert C, Thor D, Schulz A, Hofreiter M, Schoneberg T (2007). G Protein-Coupled Time Travel: Evolutionary Aspects of GPCR Research. Mol Interv, 7(1), 17-25.
     
  443. Rupf S, Jentsch H, Eschrich K (2007). Lebensraum Mundhöhle: Mikroorganismen und orale Erkrankungen. Biologie in unserer Zeit, 37(1), 51-59.
     
  444. Gebhardt R, Baldysiak-Figiel A, Krugel V, Ueberham E, Gaunitz F (2007). Hepatocellular expression of glutamine synthetase: an indicator of morphogen actions as master regulators of zonation in adult liver. Prog Histochem Cytochem, 41(4), 201-266.
     
  445. Lin Q, Weis S, Yang G, Weng YH, Helston R, Rish K, Smith A, Bordner J, Polte T, Gaunitz F, Dennery PA (2007). Heme oxygenase-1 protein localizes to the nucleus and activates transcription factors important in oxidative stress. J Biol Chem, 282(28), 20621-20633.
     
  446. Ueberham E, Aigner T, Ueberham U, Gebhardt R (2007). E-cadherin as a reliable cell surface marker for the identification of liver specific stem cells. J Mol Histol, 38(4), 359-368.
     
  447. Werth M, Gaunitz F, Gebhardt R (2007). Author Reply. Hepatology, 45(4), 1083.
     
  448. Espirito Santo S, Keiss HP, Meyer K, Buytenhek R, Roos Th, Dirsch V, Buniatian G, Ende C, Günther J, Heise K, Kellert D, Lerche K, Pavlica S, Struck F, Usbeck E, Voigt J, Zellmer S ... Gebhardt R (2007). Garlic and Cardiovascular Diseases. Med Aromat Plant Sci Biotechnol, 1(1), 25-31.
     
  449. Staubert C, Tarnow P, Brumm H, Pitra C, Gudermann T, Gruters A, Schoneberg T, Biebermann H, Rompler H (2007). Evolutionary aspects in evaluating mutations in the melanocortin 4 receptor. Endocrinology, 148(10), 4642-4648.
     
  450. Tanneberger K, Kirchberger J, Bar J, Schellenberger W, Rothemund S, Kamprad M, Otto H, Schoneberg T, Edelmann A (2007). A novel form of 6-phosphofructokinase. Identification and functional relevance of a third type of subunit in Pichia pastoris. J Biol Chem, 282(32), 23687-23697.
     
  451. Friedrichs C, Rodloff AC, Chhatwal GS, Schellenberger W, Eschrich K (2007). Rapid identification of viridans streptococci by mass spectrometric discrimination. J Clin Microbiol, 45(8), 2392-2397.
     
  452. Schoneberg T, Hermsdorf T, Engemaier E, Engel K, Liebscher I, Thor D, Zierau K, Rompler H, Schulz A (2007). Structural and functional evolution of the P2Y12-like receptor group Purinergic Signal, 3(4), 255-268.
     
  453. Lalueza-Fox C, Rompler H, Caramelli D, Staubert C, Catalano G, Hughes D, Rohland N, Pilli E, Longo L, Condemi S, de la Rasilla M, Fortea J, Rosas A, Stoneking M, Schoneberg T, Bertranpetit J, Hofreite (2007). A melanocortin 1 receptor allele suggests varying pigmentation among Neanderthals. Science, 318(5855), 1453-1455.
     
  454. Merten N, Lindner D, Rabe N, Rompler H, Morl K, Schoneberg T, Beck-Sickinger AG (2007). Receptor subtype-specific docking of Asp6.59 with C-terminal arginine residues in Y receptor ligands. J Biol Chem, 282(10), 7543-7551.
     
  455. Welt K, Weiss J, Martin R, Hermsdorf T, Drews S, Fitzl G (2007). Ginkgo biloba extract protects rat kidney from diabetic and hypoxic damage. Phytomedicine, 14(2-3), 196-203.
     
  456. Hohme S, Hengstler JG, Brulport M, Schafer M, Bauer A, Gebhardt R, Drasdo D (2007). Mathematical modelling of liver regeneration after intoxication with CCl(4). Chem Biol Interact, 168(1), 74-93.
     
  457. Barcena M, Radermacher M, Bar J, Kopperschlager G, Ruiz T (2007). The structure of the ATP-bound state of S. cerevisiae phosphofructokinase determined by cryo-electron microscopy. J Struct Biol, 159(1), 135-143.
     
  458. Schmidt H, Kunerth S, Wilms C, Strotmann R, Eilers J (2007). Spino-dendritic cross-talk in rodent Purkinje neurons mediated by endogenous Ca2+-binding proteins. J Physiol, 581(Pt 2), 619-629.
     
  459. Cohen SE, Kokkotou E, Biddinger SB, Kondo T, Gebhardt R, Kratzsch J, Mantzoros CS, Kahn CR (2007). High circulating leptin receptors with normal leptin sensitivity in liver-specific insulin receptor knock-out (LIRKO) mice. J Biol Chem, 282(32), 23672-23678.
     
  460. Weng HL, Ciuclan L, Liu Y, Hamzavi J, Godoy P, Gaitantzi H, Kanzler S, Heuchel R, Ueberham U, Gebhardt R, Breitkopf K, Dooley S (2007). Profibrogenic transforming growth factor-beta/activin receptor-like kinase 5 signaling via connective tissue growth factor expression in hepatocytes. Hepatology, 46(4), 1257-1270 .
     
  461. Benjamin S, Radermacher M, Bar J, Edelmann A, Ruiz T (2007). Structures of S. pombe phosphofructokinase in the F6P-bound and ATP-bound states. J Struct Biol, 159(3), 498-506.
     
  462. Erdmann S, Ricken A, Merkwitz C, Struman I, Castino R, Hummitzsch K, Gaunitz F, Isidoro C, Martial J, Spanel-Borowski K (2007). The expression of prolactin and its cathepsin D-mediated cleavage in the bovine corpus luteum vary with the estrous cycle. Am J Physiol Endocrinol Metab, 293(5), 1365-1377.
     
  463. Krishnamurthy V, Eschrich K, Boney A, Sullivan J, McDonald M, Kishnani PS, Koeberl DD (2007). Three successful pregnancies through dietary management of fructose-1,6-bisphosphatase deficiency. J Inherit Metab Dis, 30(5), 819-.
     
  464. Larionov S, Dedeck O, Birkenmeier G, Thal DR (2007). Expression of alpha2-macroglobulin, neutrophil elastase, and interleukin-1alpha differs in early-stage and late-stage atherosclerotic lesions in the arteries of the circle of Willis. Acta Neuropathol, 113(1), 33-43.
     
  465. Kolsch H, Larionov S, Dedeck O, Orantes M, Birkenmeier G, Griffin WS, Thal DR (2007). Association of the glutathione S-transferase omega-1 Ala140Asp polymorphism with cerebrovascular atherosclerosis and plaque-associated interleukin-1 alpha expression. Stroke, 38(10), 2847-2850.
     
  466. Plant TD, Strotmann R (2007). TRPV4: A Multifunctional Nonselective Cation Channel with Complex Regulation. In: Liedtke WB, TRP ion channel function in sensory transduction and cellular signaling cascades. (S. 125-140), Boca Raton: CRC Press.
     
  467. Zellmer S, Toepfer S, Driesch D, Woetzel D, Guthke R, Pfaff M, Gebhardt R (2007). Modelling of hepatic glutamine metabolism. In: Allgöwer F, Reuss M, Proceedings - Plenary and Contributed Papers. (S. 183-187), Stuttgart: Fraunhofer IRB Verlag.
     
  468. Schmidt-Heck W, Zellmer S, Gebhardt R, Guthke R (2007). Dynamic network reconstruction identified unexpected gene expression in primary hepatocytes after exchange of culture medium. In: Allgöwer F, Reuss M, Proceedings - Plenary and Contributed Papers. (S. 129-134), Stuttgart: Fraunhofer IRB Verlag.
     
  469. Schöneberg T (2007). Pharmakologie. In: Kiess W, Merkenschlager A, Pfäffle, R, Siekmeyer W, Therapie in der Kinder- und Jugendmedizin. (S. 3-26), München: Urban & Fischer Bei Elsevier.
     
  470. Römpler H, Schöneberg T, Strotmann R (2007). Pharmakotherapie. In: Kiess W, Merkenschlager A, Pfäffle R, Siekmeyer W., Therapie in der Kinder- und Jugendmedizin. (S. 27-139), München: Urban & Fischer bei Elsevier .
     
  471. Toepfer S, Zellmer S, Driesch D, Woetzel D, Guthke R, Gebhardt R, Pfaff M (2007). A 2-Compartment Model of Glutamine and Ammonia Metabolism in Liver Tissue. 7 New Methods and Technologies for Medicine and Biology. In: Scharff P, 52. IWK - Internationales Wissenschaftliches Kolloquium. (S. 107-112), Ilmenau: Universitätsverlag, Technische Universität/Univers.
     
  472. Böhme HJ, Eschrich, K (2007). Erkrankungen des Fructosestoffwechsels. In: Sacherl M, Hereditäre Fructoseintoleranz und Fructose-Malabsorption. (S. 48-51), Moers: Selbsthilfegruppe Hereditäre Fructoseintoleranz .
     


    473. 2006


  473. Rompler H, Rohland N, Lalueza-Fox C, Willerslev E, Kuznetsova T, Rabeder G, Bertranpetit J, Schoneberg T, Hofreiter M (2006). Nuclear gene indicates coat-color polymorphism in mammoths. Science, 313(5783), 62.
     
  474. Rompler H, Yu HT, Arnold A, Orth A, Schoneberg T (2006). Functional consequences of naturally occurring DRY motif variants in the mammalian chemoattractant receptor GPR33. Genomics, 87(6), 724-732.
     
  475. Zaki M, Schoneberg T, Al Ajrawi T, Al Said AN, Sangkuhl K, Rompler H (2006). Nephrogenic diabetes insipidus, thiazide treatment and renal cell carcinoma. Nephrol Dial Transplant, 21(4), 1082-1086.
     
  476. Engemaier E, Rompler H, Schoneberg T, Schulz A (2006). Genomic and supragenomic structure of the nucleotide-like G-protein-coupled receptor GPR34. Genomics, 87(2), 254-264.
     
  477. Römpler H, Dear PH, Krause J, Meyer M, Rohland N, Schöneberg T, Spriggs H, Stiller M, Hofreiter M (2006). Multiplex amplification of ancient DNA Nature Protocols, 1(2), 720-728.
     
  478. Tsikolia N (2006). The role and limits of a gradient based explanation of morphogenesis: a theoretical consideration. Int J Dev Biol, 50(2-3), 333-340.
     
  479. Werth M, Gebhardt R, Gaunitz F (2006). Hepatic expression of glutamine synthetase in rats is controlled by STAT5 and TCF transcription factors. Hepatology, 44(4), 967-975.
     
  480. Schulz A, Rompler H, Mitschke D, Thor D, Schliebe N, Hermsdorf T, Strotmann R, Sangkuhl K, Schoneberg T (2006). Molecular basis and clinical features of nephrogenic diabetes insipidus. Expert Rev Endocrinol Metab, 1(6), 727-741.
     
  481. Gebhardt R, Ueberham E (2006). Zonal gene expression in murine liver: Are tumors helping us to solve the mystery? Hepatology, 44(2), 512.
     
  482. Schlupper D, Giesa S, Gebhardt R (2006). Influence of biotransformation of luteolin, luteolin 7-O-glucoside, 3,4-dihydroxyflavone and apigenin by cultured rat hepatocytes on antioxidative capacity and inhibition of EGF receptor tyrosine kinase activity. Planta Med, 72(7), 596-603.
     
  483. Rupf S, Eschrich K (2006). Differenzierung oraler Bakterien mit MALDI-TOF MS. Neue Einblicke in die Entstehungsweise von Erkrankungen. Bioforum, 2, 15-17.
     
  484. Birkenmeier G, Nicklisch S, Pockelt C, Mossie A, Steger V, Glaser C, Hauschildt S, Usbeck E, Huse K, Sack U, Bauer M, Schafer A (2006). Polymyxin B-conjugated alpha 2-macroglobulin as an adjunctive therapy to sepsis: Modes of action and impact on lethality. J Pharmacol Exp Ther, 318(2), 762-771.
     
  485. Grosse J, Tarnow P, Rompler H, Schneider B, Sedlmeier R, Huffstadt U, Korthaus D, Nehls M, Wattler S, Schoneberg T, Biebermann H, Augustin M (2006). N-ethyl-N-nitrosourea-based generation of mouse models for mutant G protein-coupled receptors. Physiol Genomics, 26(3), 209-217.
     
  486. Stanchev D, Flehmig G, Gerevich Z, Norenberg W, Dihazi H, Furst S, Eschrich K, Illes P, Wirkner K (2006). Decrease of current responses at human recombinant P2X3 receptors after substitution by Asp of Ser/Thr residues in protein kinase C phosphorylation sites of their ecto-domains. Neurosci Lett, 393(1), 78-83.
     
  487. Seidel B, Bigl M, Franke H, Kittner H, Kiess W, Illes P, Krugel U (2006). Expression of purinergic receptors in the hypothalamus of the rat is modified by reduced food availability. Brain Res, 1089(1), 143-152.
     
  488. Haseloff RF, Krause E, Bigl M, Mikoteit K, Stanimirovic D, Blasig IE (2006). Differential protein expression in brain capillary endothelial cells induced by hypoxia and posthypoxic reoxygenation. Proteomics, 6(6), 1803-1809.
     
  489. Chatterjee A, Dastidar KG, Maitra S, Das-Chatterjee A, Dihazi H, Eschrich K, Majumder AL (2006). sll1981, an acetolactate synthase homologue of Synechocystis sp. PCC6803, functions as L-myo-inositol 1-phosphate synthase. Planta, 224(2), 367-379.
     
  490. Rupf S, Merte K, Eschrich K, Kneist S (2006). Streptococcus sobrinus in children and its influence on caries activity. Eur Arch Paediatr Dent, 7(1), 17-22.
     
  491. Klingmuller U, Bauer A, Bohl S, Nickel PJ, Breitkopf K, Dooley S, Zellmer S, Kern C, Merfort I, Sparna T, Donauer J, Walz G, Geyer M, Kreutz C, Hermes M, Gotschel F, Hecht A, Walter D, Egger L, Neuber (2006). Primary mouse hepatocytes for systems biology approaches: a standardized in vitro system for modelling of signal transduction pathways. IEE Proc Syst Biol, 153(6), 433-447.
     
  492. van Doorn MB, Espirito Santo SM, Meijer P, Kamerling IM, Schoemaker RC, Dirsch V, Vollmar A, Haffner T, Gebhardt R, Cohen AF, Princen HM, Burggraaf J (2006). Effect of garlic powder on C-reactive protein and plasma lipids in overweight and smoking subjects. Am J Clin Nutr, 84(6), 1324-1329.
     
  493. Kampmeier J, Baldysiak-Figiel A, de Jong-Hesse Y, Lang GK, Lang GE (2006). Effect of growth factors on proliferation and expression of growth factor receptors in a human lens epithelial cell line. J Cataract Refract Surg, 32(3), 510-514.
     
  494. Ueberham U, Ueberham E, Gruschka H, Arendt T (2006). Altered subcellular location of phosphorylated Smads in Alzheimer's disease. Eur J Neurosci, 24(8), 2327-2334.
     
  495. Ueberham U, Zobiak B, Ueberham E, Bruckner MK, Boriss H, Arendt T (2006). Differentially expressed cortical genes contribute to perivascular deposition in transgenic mice with inducible neuron-specific expression of TGF-beta1. Int J Dev Neurosci, 24(2-3), 177-186.
     
  496. Groth M, Huse K, Reichwald K, Taudien S, Hampe J, Rosenstiel P, Birkenmeier G, Schreiber S, Platzer M (2006). Method for preparing single-stranded DNA templates for Pyrosequencing using vector ligation and universal biotinylated primers. Anal Biochem, 356(2), 194-201.
     
  497. Larionov S, Dedeck O, Birkenmeier G, Orantes M, Ghebremedhin E, Thal DR (2006). The intronic deletion polymorphism of the Alpha2- macroglobulin gene modulates the severity and extent of atherosclerosis in the circle of Willis. Neuropathol Appl Neurobiol, 32(4), 451-454.
     
  498. Sorger D, Becker GA, Hauber K, Schildan A, Patt M, Birkenmeier G, Otto A, Meyer P, Kluge M, Schliebs R, Sabri O (2006). Binding properties of the cerebral alpha4beta2 nicotinic acetylcholine receptor ligand 2-[18F]fluoro-A-85380 to plasma proteins. Nucl Med Biol, 33(7), 899-906.
     
  499. Schöneberg T (2006). Endo- und parakrine Regulation der Gonadenfunktion. In: Ganten D, Ruckpaul K, Molekularmedizinische Grundlagen von para- und autokrinen Regulationsstörungen. (S. 581-605), Berlin: Springer Verlag.
     
  500. Gläser S, Birkenmeier G, Schulz S, Huse K (2006). Low Density Lipoprotein Receptor-related Protein 1 (LRP1)- one of the Hallmarks of Alzheimers Disease and other Complex Degenerative Processes. In: Welsh E, New Research on Alzheimers Disease. (S. 99-123), Hauppauge NY: Nova Science Publishers.
     
  501. Gebhardt R, Ueberham E, Gaunitz F (2006). "Glutamine synthetase as a target of beta-catenin: new insights into hepatic heterogeneity" In: Häussinger D, Kircheis G, Schliess F, "Hepatic Encephalopathy and Nitrogen Metabolism" (S. 395-405), Dortrecht: Springer Verlag.
     
  502. Zellmer S, Schmidt-Heck W, Gaunitz F, Baldysiak-Figiel A, Guthke R, Gebhardt R (2006). "Dynamic network reconstruction from gene expression data describing the effect of LiCl stimulation on hepatocytes" In: Hofestädt R, Integrative Bioinformatics: Yearbook 2005. (S. 39-54), Aachen: Shaker Verlag.
     
  503. Guthke R, Schmidt-Heck W, Pless G, Gebhardt R, Pfaff M, Gerlach JC, Zeilinger K (2006). "Dynamic Model of Amino Acid and Carbohydrate Metabolism in Primary Human Liver Cells" In: Maglaveras N et al., Lecture notes in computer science: 4345: (S. 137-149), Berlin Heidelberg: Springer Verlag.
     


    504. 2005


  504. Baumgart Y, Otto A, Schafer A, Usbeck E, Cott C, Schott A, Tornack M, Wenzel A, Mossie A, Birkenmeier G (2005). Characterization of Novel Monoclonal Antibodies for Prostate-Specific Antigen (PSA) with Potency to Recognize PSA Bound to {alpha}2-Macroglobulin. Clin Chem, 51(1), 84-92.
     
  505. Baldysiak-Figiel A, Jong-Hesse YD, Lang GK, Lang GE (2005). Octreotide inhibits growth factor-induced and basal proliferation of lens epithelial cells in vitro. J Cataract Refract Surg, 31, 1059-1064.
     
  506. Schöneberg T (2005). Krankheitsrelevante Mutationen in G-Protein-gekoppelten Rezeptoren. BIOforum, 28(5), 28-30.
     
  507. Sangkuhl K, Rompler H, Busch W, Karges B, Schoneberg T (2005). Nephrogenic diabetes insipidus caused by mutation of Tyr205: a key residue of V2 vasopressin receptor function. Hum Mutat, 25(5), p505 (7 S.).
     
  508. Gaunitz F, Deichsel D, Heise K, Werth M, Anderegg U, Gebhardt R (2005). An intronic silencer element is responsible for specific zonal expression of glutamine synthetase in the rat liver. Hepatology, 41(6), 1225-1232.
     
  509. Hannemann A, Jandrig B, Gaunitz F, Eschrich K, Bigl M (2005). Characterization of the human P-type 6-phosphofructo-1-kinase gene promoter in neural cell lines. Gene, 345(2), 237-247.
     
  510. Richter W, Hermsdorf T, Dettmer D (2005). Renaturation of the catalytic domain of PDE4A expressed in Escherichia coli as inclusion bodies. Methods Mol Biol, 307, 155-165.
     
  511. Pavlica S, Gebhardt R (2005). Protective effects of ellagic and chlorogenic acids against oxidative stress in PC12 cells. Free Radic Res, 39(12), 1377-1390.
     
  512. Arendt E, Ueberham U, Bittner R, Gebhardt R, Ueberham E (2005). Enhanced matrix degradation after withdrawal of TGF-beta1 triggers hepatocytes from apoptosis to proliferation and regeneration. Cell Prolif, 38(5), 287-299.
     
  513. Rompler H, Schulz A, Pitra C, Coop G, Przeworski M, Paabo S, Schoneberg T (2005). The rise and fall of the chemoattractant receptor GPR33. J Biol Chem, 280(35), 31068-31075.
     
  514. Dihazi H, Kessler R, Muller GA, Eschrich K (2005). Lysine 3 acetylation regulates the phosphorylation of yeast 6-phosphofructo-2-kinase under hypo-osmotic stress. Biol Chem, 386(9), 895-900.
     
  515. Rupf S, Breitung K, Schellenberger W, Merte K, Kneist S, Eschrich K (2005). Differentiation of mutans streptococci by intact cell matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Oral Microbiol Immunol, 20(5), 267-273.
     
  516. Frenzel J, Richter J, Eschrich K (2005). Pyruvate protects glucose-deprived Muller cells from nitric oxide-induced oxidative stress by radical scavenging. Glia, 52(4), 276-288.
     
  517. Kaetzke A, Jentzsch D, Eschrich K (2005). Quantification of Microthrix parvicella in activated sludge bacterial communities by real-time PCR. Lett Appl Microbiol, 40(3), 207-211.
     
  518. Edelmann A, Kruger M, Schmid J (2005). Genetic relationship between human and animal isolates of Candida albicans. J Clin Microbiol, 43(12), 6164-6166.
     
  519. Sack U, Hirth A, Funke B, Wiedemeyer K, Lange F, Troltzsch M, Tannapfel A, Gebhardt R, Emmrich F, Lehmann J (2005). A novel model of fibroblast-mediated cartilage destruction. Scand J Immunol, 61(1), 18-28.
     
  520. Schulz S, Kohler K, Schagdarsurengin U, Greiser P, Birkenmeier G, Muller-Werdan U, Werdan K, Glaser C (2005). The human FGF2 level is influenced by genetic predisposition. Int J Cardiol, 101(2), 265-271.
     
  521. Fischer S, Drenckhahn C, Wolf C, Eschrich K, Kellermann S, Froster UG, Schober R (2005). Clinical significance and neuropathology of primary MADD in C34-T and G468-T mutations of the AMPD1 gene. Clin Neuropathol, 24(2), 77-85.
     
  522. Danielyan L, Mueller L, Proksch B, Kabisch D, Weller M, Wiesinger H, Buniatian GH, Gleiter CH (2005). Similar protective effects of BQ-123 and erythropoietin on survival of neural cells and generation of neurons upon hypoxic injury. Eur J Cell Biol, 84, 907-913.
     
  523. Gerber M, Boettner A, Seidel B, Lammert A, Bar J, Schuster E, Thiery J, Kiess W, Kratzsch J (2005). Serum resistin levels of obese and lean children and adolescents: biochemical analysis and clinical relevance. J Clin Endocrinol Metab, 90(8), 4503-4509.
     
  524. Milenkovic I, Birkenmeier G, Wiedemann P, Reichenbach A, Bringmann A (2005). Effect of alpha2-macroglobulin on retinal glial cell proliferation. Graefes Arch Clin Exp Ophthalmol, 243(8), 811-816.
     
  525. Ueberham U, Ueberham E, Bruckner MK, Seeger G, Gartner U, Gruschka H, Gebhardt R, Arendt T (2005). Inducible neuronal expression of transgenic TGF-beta1 in vivo: dissection of short-term and long-term effects. Eur J Neurosci, 22(1), 50-64.
     
  526. Kruithof-de Julio M, Labruyere WT, Ruijter JM, Vermeulen JL, Stanulovic V, Stallen JM, Baldysiak-Figiel A, Gebhardt R, Lamers WH, Hakvoort TB (2005). The RL-ET-14 cell line mediates expression of glutamine synthetase through the upstream enhancer/promoter region. J Hepatol, 43(1), 126-131.
     
  527. Rupf S, Brader I, Vonderlind D, Kannengiesser S, Eschrich K, Roeder I, Merte K (2005). In Vitro, Clinical, and Microbiological Evaluation of a Linear Oscillating Device for Scaling and Root Planing. J Periodontol, 76(11), 1942-1949.
     
  528. Rakus D, Maciaszczyk E, Wawrzycka D, Ulaszewski S, Eschrich K, Dzugaj A (2005). The origin of the high sensitivity of muscle fructose 1,6-bisphosphatase towards AMP. FEBS Lett, 579(25), 5577-5581.
     
  529. Wirkner K, Stanchev D, Koles L, Klebingat M, Dihazi H, Flehmig G, Vial C, Evans RJ, Furst S, Mager PP, Eschrich K, Illes P (2005). Regulation of human recombinant P2X3 receptors by ecto-protein kinase C. J Neurosci, 25(34), 7734-7742.
     
  530. Schöneberg T, Sangkuhl K, Römpler H, Schulz A (2005). Enzyme-linked immunosorbent assays as tools in studying interactions of G-protein-coupled receptors. In: George SR, O'Dowd BF, G Protein-Coupled Receptor–Protein Interactions (S. 257-277), Hoboken: John Wiley & Sons, Inc..
     
  531. Gebhardt R (2005). Choleretic and anticholestatic activities of flavonoids of artichoke (Cynara cardunculus L. subsp. scolymus (L.) Hayek) In: Bianco VV, Calabrese N, Rubatzky V, Acta Horticulturae No. 681 Proceedings of the fourth international congress on artichoke. (S. 429-435), Leuven: ISHS Secretariat,.
     


    532. 2004


  532. Dihazi H, Kessler R, Eschrich K (2004). High osmolarity glycerol (HOG) pathway-induced phosphorylation and activation of 6-phosphofructo-2-kinase are essential for glycerol accumulation and yeast cell proliferation under hyperosmotic stress. J Biol Chem, 279(23), 23961-23968.
     
  533. Gross P, Schöneberg T (2004). Rescue of protein mutants: why? Nephrol Dial Transplant, 5, 1029-1032.
     
  534. Sangkuhl K, Schulz A, Römpler H, Yun J, Wess J, Schöneberg T (2004). Aminoglycoside-mediated rescue of a disease-causing nonsense mutation in the V2 vasopressin receptor gene in vitro and in vivo. Hum Mol Genet, 9, 893-903.
     
  535. Gaunitz F, Heise K, Gebhardt R (2004). A silencer element in the first intron of the glutamine synthetase gene represses induction by glucocorticoids. Mol Endocrinol, 18(1), 63-69.
     
  536. Gaunitz, F, Heise, K (2004). Zellbasierte Assays zur HTS-kompatiblen Bestimmung von Zytotoxizität, Apoptose und Vitalität in Diagnose, Produktentwicklung und im Forschungslabor. BIOspektrum, 10(2), 214-215.
     
  537. Ueberham E, Arendt E, Starke M, Bittner R, Gebhardt R (2004). Reduction and expansion of the glutamine synthetase expressing zone in livers from tetracycline controlled TGF-beta1 transgenic mice and multiple starved mice. J Hepatol, 41(1), 75-81.
     
  538. Nissler L, Gebhardt R, Berger S (2004). Flavonoid binding to a multi-drug-resistance transporter protein: an STD-NMR study. Anal Bioanal Chem, 379, 1045-1049.
     
  539. Ende C, Gebhardt R (2004). Inhibition of matrix metalloproteinase-2 and -9 activities by selected flavonoids. Planta Med, 70, 1006-1008.
     
  540. Meyer K, Ueberham E, Gebhardt R (2004). Influence of organosulphur compounds from garlic on the secretion of matrix metalloproteinases and their inhibitor TIMP-1 by cultured HUVEC cells. Cell Biol Toxicol, 20, 253-260.
     
  541. Theiss C, Bohley P, Bisswanger H, Voigt J (2004). Uptake of polyamines by the unicellular green alga Chlamydomonas reinhardtii and their effect on ornithine decarboxylase activity. J Plant Physiol, 161(1), 3-14.
     
  542. Voigt J, Stevanovic S, Schirle M, Fausel M, Maier J, Adam KH, Marquardt O (2004). A 14-3-3 protein of Chlamydomonas reinhardtii associated with the endoplasmic reticulum: nucleotide sequence of the cDNA and the corresponding gene and derived amino acid sequence. Biochim Biophys Acta, 1679(2), 180-194.
     
  543. Baldysiak-Figiel A, Lang GK, Kampmeier J, Lang GE (2004). Octreotide prevents growth factor-induced proliferation of bovine retinal endothelial cells under hypoxia. J Endocrinol, 180(3), 417-424.
     
  544. Sinnreich O, Kratzsch J, Reichenbach A, Glaser C, Huse K, Birkenmeier G (2004). Plasma levels of transforming growth factor-1beta and alpha2-macroglobulin before and after radical prostatectomy: association to clinicopathological parameters. Prostate, 61(3), 201-208.
     
  545. Glaser C, Schulz S, Handschug K, Huse K, Birkenmeier G (2004). Genetic and functional characteristics of the human in vivo LRP1/A2MR receptor suggested as a risk marker for Alzheimer's disease and other complex (degenerative) diseases. Neurosci Res, 50(1), 85-101.
     
  546. Schoneberg T, Schulz A, Biebermann H, Hermsdorf T, Rompler H, Sangkuhl K (2004). Mutant G-protein-coupled receptors as a cause of human diseases. Pharmacol Ther, 104(3), 173-206.
     
  547. Schwock J, Kirchberger J, Edelmann A, Kriegel TM, Kopperschlager G (2004). Interaction of 6-phosphofructokinase with cytosolic proteins of Saccharomyces cerevisiae. Yeast, 21(6), 483-494.
     
  548. Mueller P, Horn LC, Buehrdel P, Boehme HJ (2004). Hydropericardium causing sudden infant death in glycogenosis type I: Osmotic injury due to percutaneous silastic catheterization Klin Padiatr , 216(5), 294-296.
     
  549. Kneist S, Heinrich-Weltzien R, Rupf S, Merte K, Eschrich K (2004). Zur Bedeutung von S. sobrinus für die Kariesentwicklung bei Kindern. Oralprophylaxe, 26(1), 24-28.
     
  550. Hollborn M, Krausse C, Iandiev I, Yafai Y, Tenckhoff S, Bigl M, Schnurrbusch UE, Astrid Limb G, Reichenbach A, Kohen L, Wolf S, Wiedemann P, Bringmann A (2004). Glial cell expression of hepatocyte growth factor in vitreoretinal proliferative disease. Lab Invest, 84(8), 963-972.
     
  551. Blasko I, Beer R, Bigl M, Apelt J, Franz G, Rudzki D, Ransmayr G, Kampfl A, Schliebs R (2004). Experimental traumatic brain injury in rats stimulates the expression, production and activity of Alzheimer's disease beta-secretase (BACE-1). J Neural Transm, 111(4), 523-536.
     
  552. Bojarski C, Weiske J, Schöneberg T, Schröder W, Mankertz J, Schulzke JD, Florian P, Fromm M, Tauber R, Huber O (2004). The specific fates of tight junction proteins in apoptotic epithelial cells. J Cell Sci, 117, 2097-2107.
     
  553. Fuchs S, Kapp T, Otto H, Schöneberg T, Franke P, Gust R, Schlüter AD (2004). A surface-modified dendrimer set for potential application as drug delivery vehicles: synthesis, in vitro toxicity, and intracellular localization. Chemistry, 10(5), 1167-1192.
     
  554. Teich L, Daub KS, Krugel V, Nissler L, Gebhardt R, Eger K (2004). Synthesis and biological evaluation of new derivatives of emodin. Bioorg Med Chem, 12(22), 5961-5971.
     
  555. Scheidt HA, Pampel A, Nissler L, Gebhardt R, Huster D (2004). Investigation of the membrane localization and distribution of flavonoids by high-resolution magic angle spinning NMR spectroscopy. Biochim Biophys Acta, 1663(1-2), 97-107.
     
  556. Hollborn M, Birkenmeier G, Saalbach A, Iandiev I, Reichenbach A, Wiedemann P, Kohen L (2004). Expression of LRP1 in retinal pigment epithelial cells and its regulation by growth factors. Invest Ophthalmol Vis Sci, 45(6), 2033-2038.
     
  557. Apelt J, Bigl M, Wunderlich P, Schliebs R (2004). Aging-related increase in oxidative stress correlates with developmental pattern of beta-secretase activity and beta-amyloid plaque formation in transgenic Tg2576 mice with Alzheimer-like pathology. Int J Dev Neurosci, 22(7), 475-484.
     
  558. Welt K, Weiss J, Martin R, Dettmer D, Hermsdorf T, Asayama K, Meister S, Fitzl G (2004). Ultrastructural, immunohistochemical and biochemical investigations of the rat liver exposed to experimental diabetes und acute hypoxia with and without application of Ginkgo extract. Exp Toxicol Pathol, 55(5), 331-345.
     
  559. Fleischmann BK, Duan Y, Fan Y, Schöneberg T, Ehlich A, Lenka N, Viatchenko-Karpinski S, Pott L, Hescheler J, Fakler B (2004). Differential subunit composition of the G protein-activated inward-rectifier potassium channel during cardiac development. J Clin Invest, 114(7), 994-1001.
     
  560. Schöneberg T (2004). Nephrogenic diabetes insipidus In: Martini L, The encyclopedia of endocrinology and endocrine diseases (S. 651-654), San Diego: Academic Press.
     
  561. Schöneberg T (2004). Tolerance and desensitization In: Offermanns S, Rosenthal W, Encyclopedic Reference of Molecular Pharmacology (S. 913-916), Berlin: Springer Verlag.