2024


  1. Tietze L, Christ M, Yu J, Stock P, Nickel S, Schulze A, Bartels M, Tautenhahn HM, Christ B (2024). Approaching Thrombospondin-1 as a Potential Target for Mesenchymal Stromal Cells to Support Liver Regeneration after Partial Hepatectomy in Mouse and Humans. Cells, 13(6), 529.
     


    2. 2023


  2. Lindström S, Wang L, Feng H, Majumdar A, Huo S, Macdonald J, Harrison T, Turman C, Chen H, Mancuso N, Bammler T, Gallinger S, Gruber SB, Gunter MJ, Le Marchand L, Moreno V, Offit K, De Vivo I, O'Mara TA, Spurdle AB, Tomlinson I, Fitzgerald R, Gharahkhani P, Gockel I, Jankowski J, Macgregor S, Schumacher J, Barnholtz-Sloan J, Bondy ML, Houlston RS, Jenkins RB, Melin B, Wrensch M, Brennan P, Christiani DC, Johansson M, Mckay J, Aldrich MC, Amos CI, Landi MT, Tardon A, Bishop DT, Demenais F, Goldst (2023). Genome-wide analyses characterize shared heritability among cancers and identify novel cancer susceptibility regions. J Natl Cancer Inst, 115(6), 712-732.
     
  3. Rainer Porschen, Wolfgang Fischbach, Ines Gockel, Stephan Hollerbach, Arnulf Hölscher, Petra Lynen Jansen, Stephan Miehlke, Oliver Pech, Michael Stahl, Udo Vanhoefer, Matthias P A Ebert, Gustavo Baretton, Tilmann Bostel, Christian Ell, Ute Goerling, Lars Grenacher, Barbara Kade, Wolfram Trudo Knoefel, Jürgen Körber, Philipp Lenz, Florian Lordick, Dietmar Lorenz, Sylvie Lorenzen, Alexander Meining, Josef Menzel, Helmut Messmann, Hans-Joachim Meyer, Stefan Paul Mönig, Ute Nöthlings, Heinz Schmidbe (2023). S3-Leitlinie Diagnostik und Therapie der Plattenepithelkarzinome und Adenokarzinome des Ösophagus. Z Gastroenterol, 61(6), 701-745.
     
  4. Rainer Porschen, Wolfgang Fischbach, Ines Gockel, Stephan Hollerbach, Arnulf Hölscher, Petra Lynen Jansen, Stephan Miehlke, Oliver Pech, Michael Stahl, Udo Vanhoefer, Matthias P A Ebert, Gustavo Baretton, Tilmann Bostel, Christian Ell, Ute Goerling, Lars Grenacher, Barbara Kade, Wolfram Trudo Knoefel, Jürgen Körber, Philipp Lenz, Florian Lordick, Dietmar Lorenz, Sylvie Lorenzen, Alexander Meining, Josef Menzel, Helmut Messmann, Hans-Joachim Meyer, Stefan Paul Mönig, Ute Nöthlings, Heinz Schmidbe (2023). S3-Leitlinie Diagnostik und Therapie der Plattenepithelkarzinome und Adenokarzinome des Ösophagus. Z Gastroenterol, 61(6), 209-307.
     


    5. 2022


  5. Christ B, Dahmen U, Radde N, Ricken T (2022). Editorial: Computational Modeling for Liver Surgery and Interventions Frontiers in Physiology, 13, 859522.
     
  6. Nickel S, Christ M, Schmidt S, Kosacka J, Kühne H, Roderfeld M, Longerich T, Tietze L, Bosse I, Hsu M-J, Stock P, Roeb E, Christ B (2022). Human Mesenchymal Stromal Cells Resolve Lipid Load in High Fat Diet-Induced Non-Alcoholic Steatohepatitis in Mice by Mitochondria Donation Cells, 11, 1829.
     
  7. Koch M, Nickel S, Lieshout R, Lissek SM, Leskova M, van der Laan LJW, Verstegen MMA, Christ B, Pampaloni F (2022). Label-Free Imaging Analysis of Patient-Derived Cholangiocarcinoma Organoids after Sorafenib Treatment Cells, 11(22), 3613.
     
  8. Helmrich N, Roderfeld M, Baier A, Windhorst A, Herebian D, Mayatepek E, Dierkes C, Ocker M, Glebe D, Christ B, Churin Y, Irungbam K, Roeb E (2022). Pharmacologic Antagonization of Cannabinoid Receptor 1 Improves Cholestasis in Abcb4-/- Mice. Cell Mol Gastroenterol Hepatol, 13(4), 1041-1055.
     
  9. Albadry M, Höpfl S, Ehteshamzad N, König M, Böttcher M, Neumann J, Lupp A, Dirsch O, Radde N, Christ B, Christ M, Schwen LO, Laue H, Klopfleisch R, Dahmen U (2022). Periportal steatosis in mice affects distinct parameters of pericentral drug metabolism Sci Rep, 12, 21825.
     


    10. 2021


  10. Hsu MJ, Christ M, Christ B (2021). Co-Culture of Human Mesenchymal Stromal Cells and Primary Mouse Hepatocytes. Methods Mol Biol, 2269, 151-165.
     
  11. Christ B, Collatz M, Dahmen U, Herrmann KH, Höpfl S, König M, Lambers L, Marz M, Meyer D, Radde N, Reichenbach JR, Ricken T, Tautenhahn HM (2021). Hepatectomy-Induced Alterations in Hepatic Perfusion and Function - Toward Multi-Scale Computational Modeling for a Better Prediction of Post-hepatectomy Liver Function Frontiers in Physiology, 12, 733868.
     
  12. Nickel S, Vlaic S, Christ M, Schubert K, Henschler R, Tautenhahn F, Burger C, Kühne H, Erler S, Roth A, Wild C, Brach J, Hammad S, Gittel C, Baunack M, Lange U, Broschewitz J, Stock P, Metelmann I, Bartels M, Pietsch U-C, Krämer S, Eichfeld U, von Bergen M, Dooley S, Tautenhahn H-M, Christ B (2021). Mesenchymal stromal cells mitigate liver damage after extended resection in the pig by modulating thrombospondin-1/TGF-? npj regenerative medicine, 6, 84.
     
  13. Nickel S, Christ B (2021). Greasy hair against obesity Signal Transduction and Targeted Therapy, 6, 429.
     


    14. 2020


  14. Hsu MJ, Karkossa I, Schäfer I, Christ M, Kühne H, Schubert K, Rolle-Kampczyk UE, Kalkhof S, Nickel S, Seibel P, von Bergen M, Christ B (2020). Mitochondrial Transfer by Human Mesenchymal Stromal Cells Ameliorates Hepatocyte Lipid Load in a Mouse Model of NASH. Biomedicines, 8(9), E350.
     


    15. 2019


  15. Winkler S, Hempel M, Hsu MJ, Gericke M, Kuhne H, Bruckner S, Erler S, Burkhardt R, Christ B (2019). Immune-Deficient Pfp/Rag2-/- Mice Featured Higher Adipose Tissue Mass and Liver Lipid Accumulation with Growing Age than Wildtype C57BL/6N Mice. Cells, 8(775), 1-22.
     
  16. Hartwig V, Dewidar B, Lin T, Dropmann A, Ganss C, Kluth MA, Tappenbeck N, Tietze L, Christ B, Frank M, Vogelmann R, Ebert MPA, Dooley S (2019). Human skin-derived ABCB5+ stem cell injection improves liver disease parameters in Mdr2KO mice. Arch Toxicol, 93(9), 2645-2660.
     
  17. Hartwig V, Dewidar B, Lin T, Dropmann A, Ganss C, Kluth MA, Tappenbeck N, Tietze L, Christ B, Frank MH, Vogelmann R, Ebert MPA, Dooley S (2019). Correction to: Human skin-derived ABCB5+ stem cell injection improves liver disease parameters in Mdr2KO mice. Arch Toxicol, 93(12), 3669-3670.
     


    18. 2018


  18. Tietze L, Winkler S, Hempel M, Kluth MA, Tappenbeck N, Ganss C, Dooley S, Christ B (2018). Assessment of the hepatocytic differentiation ability of human skin-derived ABCB5+ stem cells. Exp Cell Res, 369(2), 335-347.
     
  19. Uder C, Bruckner S, Winkler S, Tautenhahn HM, Christ B (2018). Mammalian MSC from selected species: Features and applications. Cytometry A, 93(1), 32-49.
     


    20. 2017


  20. Tautenhahn HM, Bruckner S, Uder C, Erler S, Hempel M, von Bergen M, Brach J, Winkler S, Pankow F, Gittel C, Baunack M, Lange U, Broschewitz J, Dollinger M, Bartels M, Pietsch U, Amann K, Christ B (2017). Mesenchymal stem cells correct haemodynamic dysfunction associated with liver injury after extended resection in a pig model. Sci Rep, 7(1), 2617.
     
  21. Stock P, Bielohuby M, Staege MS, Hsu MJ, Bidlingmaier M, Christ B (2017). Impairment of Host Liver Repopulation by Transplanted Hepatocytes in Aged Rats and the Release by Short-Term Growth Hormone Treatment. Am J Pathol, 187(3), 553-569.
     
  22. Christ B, Dahmen U, Herrmann KH, Konig M, Reichenbach JR, Ricken T, Schleicher J, Ole Schwen L, Vlaic S, Waschinsky N (2017). Computational Modeling in Liver Surgery. Front Physiol, 8, 906.
     
  23. Bruckner S, Zipprich A, Hempel M, Thonig A, Schwill F, Roderfeld M, Roeb E, Christ B (2017). Improvement of portal venous pressure in cirrhotic rat livers by systemic treatment with adipose tissue-derived mesenchymal stromal cells. Cytotherapy, 19(12), 1462-1473.
     
  24. Christ B, Franquesa M, Najimi M, van der Laan LJW, Dahlke MH (2017). Cellular and Molecular Mechanisms of Mesenchymal Stem Cell Actions. Stem Cells Int, 2017, 2489041.
     


    25. 2016


  25. Tautenhahn HM, Bruckner S, Baumann S, Winkler S, Otto W, von Bergen M, Bartels M, Christ B (2016). Attenuation of Postoperative Acute Liver Failure by Mesenchymal Stem Cell Treatment Due to Metabolic Implications. Ann Surg, 263(3), 546-556.
     
  26. Winkler S, Hempel M, Bruckner S, Tautenhahn HM, Kaufmann R, Christ B (2016). Identification of Pathways in Liver Repair Potentially Targeted by Secretory Proteins from Human Mesenchymal Stem Cells. Int J Mol Sci, 17(7), E1099.
     
  27. Stock P, Christ B (2016). Methods in Molecular Biology - Hepatocyte Transplantation. In: Stock P, Christ B, Methods in Molecular Biology - Hepatocyte Transplantation. (S. 1-365), New York: Springer Verlag.
     


    28. 2015


  28. Hempel M, Schmitz A, Winkler S, Kucukoglu O, Bruckner S, Niessen C, Christ B (2015). Pathological implications of cadherin zonation in mouse liver. Cell Mol Life Sci, 72(13), 2599-2612.
     
  29. Christ B, Bruckner S, Winkler S (2015). The Therapeutic Promise of Mesenchymal Stem Cells for Liver Restoration. Trends Mol Med, 21(11), 673-686.
     
  30. Winkler S, Hempel M, Bruckner S, Mallek F, Weise A, Liehr T, Tautenhahn HM, Bartels M, Christ B (2015). Mouse white adipose tissue-derived mesenchymal stem cells gain pericentral and periportal hepatocyte features after differentiation in vitro, which are preserved in vivo after hepatic transplantation. Acta Physiol (Oxf), 215(2), 89-104.
     
  31. Walldorf J, Hermann M, Porzner M, Pohl S, Metz H, Mader K, Zipprich A, Christ B, Seufferlein T (2015). In-vivo monitoring of acute DSS-Colitis using Colonoscopy, high resolution Ultrasound and bench-top Magnetic Resonance Imaging in Mice. Eur Radiol, 25(10), 2984-2991.
     


    32. 2014


  32. Bruckner S, Tautenhahn HM, Winkler S, Stock P, Dollinger M, Christ B (2014). A fat option for the pig: Hepatocytic differentiated mesenchymal stem cells for translational research. Exp Cell Res, 321(2), 267-75.
     
  33. Winkler S, Borkham-Kamphorst E, Stock P, Brückner S, Dollinger M, Weiskirchen R, Christ B (2014). Human mesenchymal stem cells towards non-alcoholic steatohepatitis in an immunodeficient mouse model. Exp Cell Res, 326(2), 230-239.
     
  34. Stock P, Brückner S, Winkler S, Dollinger MM, Christ B (2014). Human bone marrow mesenchymal stem cell-derived hepatocytes improve the mouse liver after acute acetaminophen intoxication by preventing progress of injury. Int J Mol Sci, 15(4), 7004-7028.
     
  35. Hammad S, Hoehme S, Friebel A, von Recklinghausen I, Othman A, Begher-Tibbe B, Reif R, Godoy P, Johann T, Vartak A, Golka K, Bucur PO, Vibert E, Marchan R, Christ B, Dooley S, Meyer C, et al. (2014). Protocols for staining of bile canalicular and sinusoidal networks of human, mouse and pig livers, three-dimensional reconstruction and quantification of tissue microarchitecture by image processing and analysis. Arch Toxicol, 88(5), 1161-1183.
     
  36. Christ B (2014). Treatment of NASH with human mesenchymal stem cells in the immunodeficient mouse. In: Christ B, Oerlecke J, Stock P, Animal models for stem cell therapy. Schriftenreihe: Methods in molecular biology. (S. 51-56), New York: Humana Press.
     


    37. 2013


  37. Bruckner S, Tautenhahn HM, Winkler S, Stock P, Jonas S, Dollinger M, Christ B (2013). Isolation and hepatocyte differentiation of mesenchymal stem cells from porcine bone marrow - "surgical waste" as a novel MSC source. Transplant Proc, 45(5), 2056-2058.
     
  38. Christ B, Pelz S (2013). Implication of hepatic stem cells in functional liver repopulation. Cytometry A, 83(1), 90-102.
     
  39. Christ B, Rumpf D (2013). Was passiert mit dem Butterbrot nach dem Essen? In: Rumpf D, 1, 2, 3 ... Warum hört das Zählen nie auf?: Grundschulkinder fragen und forschen im Unterricht. (S. 85-96), Seelze: Klett/Kallmeyer (Friedrich Verlag).
     


    40. 2012


  40. Pelz S, Stock P, Bruckner S, Christ B (2012). A methionine-choline-deficient diet elicits NASH in the immunodeficient mouse featuring a model for hepatic cell transplantation. Exp Cell Res, 318(3), 276-287.
     
  41. Christ B, Bruckner S (2012). Rodent animal models for surrogate analysis of cell therapy in acute liver failure. Front Physiol, 3, 78.
     
  42. Christ B, Stock P (2012). Mesenchymal stem cell-derived hepatocytes for functional liver replacement. Front Immunol, 3, 168.
     
  43. Sawitzky M, Zeissler A, Langhammer M, Bielohuby M, Stock P, Hammon HM, Gors S, Metges CC, Stoehr BJ, Bidlingmaier M, Fromm-Dornieden C, Baumgartner BG, Christ B, Brenig B, Binder G, Metzger F, Renne U (2012). Phenotype selection reveals coevolution of muscle glycogen and protein and PTEN as a gate keeper for the accretion of muscle mass in adult female mice. PLoS One, 7(6), e39711.
     


    44. 2011


  44. Christ B, Bruckner S, Stock P (2011). Hepatic transplantation of mesenchymal stem cells in rodent animal models. Methods Mol Biol, 698, 315-330.
     
  45. Christ B, Dollinger MM (2011). The generation of hepatocytes from mesenchymal stem cells and engraftment into the liver. Curr Opin Organ Transplant, 16(1), 69-75.
     
  46. Christ B, Stock P, Dollinger MM (2011). CD13: Waving the flag for a novel cancer stem cell target. Hepatology, 53(4), 1388-1390.
     
  47. Christoforou C, Schütz T, Paulisch E, Peroz I (2011). Osteoporose: Was ist wichtig für den Zahnarzt? Zahnärzteblatt Sachsen, 5, 27-30.
     
  48. Bielohuby M, Menhofer D, Kirchner H, Stoehr BJ, Muller TD, Stock P, Hempel M, Stemmer K, Pfluger PT, Kienzle E, Christ B, Tschop MH, Bidlingmaier M (2011). Induction of ketosis in rats fed low-carbohydrate, high-fat diets depends on the relative abundance of dietary fat and protein. Am J Physiol Endocrinol Metab, 300(1), 65-76.
     
  49. Bielohuby M, Sawitzky M, Stoehr BJ, Stock P, Menhofer D, Ebensing S, Bjerre M, Frystyk J, Binder G, Strasburger C, Wu Z, Christ B, Hoeflich A, Bidlingmaier M (2011). Lack of dietary carbohydrates induces hepatic growth hormone (GH) resistance in rats. Endocrinology, 152(5), 1948-1960.